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Invitrogen
Claudin 8 Recombinant Superclonal Antibody (6HCLC)
FIGURE: 1 / 1
Claudin 8 Antibody (710223) in WB
Western blot analysis of Claudin-8 in whole cell extracts of HEK293 using a Claudin-8 Recombinant Rabbit Polyclonal Antibody (Product # 710223) at a dilution of 2 µg/mL. Samples were detected using chemiluminescence (ECL). Results show a band at ~25kDa.
Product Details
710223
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Clone
6HCLC
Immunogen
Peptide corresponding to amino acids 206-225 of human claudin-8
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2532635
Product Specific Information
This antibody is predicted to react with equine, mouse and rat based on sequence homology.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Target Information
Claudin-8 belongs to the claudin family of integral membrane proteins. Claudins are responsible for the formation of tight junction strands, and are connected with the actin cytoskeleton mediated by ZO-1. Claudin-8 is a tight junction protein expressed in several distal nephron segments, suggesting that it may have a role as a paracellular cation barrier protein. Claudin-8 is expressed in the inner ear, and the umbrella cell tight junctions in the bladder epithelium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Claudin-8; epididymis secretory protein Li 79
Gene Aliases: CLDN8; HEL-S-79; UNQ779/PRO1573
UniProt ID: (Human) P56748
Entrez Gene ID: (Human) 9073
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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