Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA1-26148
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length, native protein extracted and purified from mouse tumor tissues.
Conjugate
Form
Liquid
Concentration
3 mg/mL
Purification
Ion-exchange chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10977210
Product Specific Information
This antibody does not react with mouse collagen types I and III, human collagen types IV and V, mouse fibronectin or mouse laminin.
Target Information
Collagen IV is a type of collagen protein that is a major component of the basement membrane in various tissues, including the kidneys, lungs, and skin. It forms a network-like structure that provides support and stability to the surrounding tissue. Collagen IV is composed of three alpha chains, which are encoded by the COL4A1, COL4A2, and COL4A3 genes. Mutations in these genes can lead to various genetic disorders, such as Alport syndrome and Goodpasture syndrome, which affect the kidneys and lungs, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha1(IV) collagen; canstatin; col4a3; col4a4; Collagen 4; Collagen alpha-1(IV) chain; Collagen alpha-2(IV) chain; Collagen alpha-3(IV) chain; Collagen alpha-4(IV) chain; collagen alpha-5(IV) chain; collagen alpha-6(IV) chain; collagen type IV alpha3 chain; collagen type IV alpha5 chain; Del(8)Bru44H; procollagen type IV alpha 5; procollagen type IV alpha 6; procollagen, type IV, alpha 1; procollagen, type IV, alpha 2; procollagen, type IV, alpha 3; procollagen, type IV, alpha 4; procollagen, type IV, alpha 5; procollagen, type IV, alpha 6; retinal anterior wiring; tumstatin; Type IV Collagen
Gene Aliases: [a]3(IV); [a]4(IV); alpha3(IV); BB116301; Bru; Col4a-1; Col4a-2; Col4a1; Col4a2; Col4a3; Col4a4; Del(8)44H; E130010M05Rik; Raw; Svc
UniProt ID: (Mouse) P02463, (Mouse) P08122, (Mouse) Q9QZS0, (Mouse) Q9QZR9
Entrez Gene ID: (Mouse) 12826, (Mouse) 12827, (Mouse) 12828, (Mouse) 12829, (Mouse) 12830, (Mouse) 94216
angiogenesis
patterning of blood vessels
brain development
neuromuscular junction development
blood vessel morphogenesis
retinal blood vessel morphogenesis
renal tubule morphogenesis
cellular response to amino acid stimulus
basement membrane organization
transcription, DNA-templated
negative regulation of angiogenesis
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell adhesion
cell surface receptor signaling pathway
cell proliferation
glomerular basement membrane development
endothelial cell apoptotic process
extracellular matrix organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support