Proteintech

Collagen Type III (N-terminal) Polyclonal Antibody

Collagen Type III (N-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 15

Collagen Type III (N-terminal) Antibody (22734-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using 22734-1-AP (Collagen Type III (N-terminal) antibody) at dilution of 1:1000 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Collagen Type III (N-terminal) Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Collagen Type III (N-terminal) Antibody in Western Blot (WB)

Collagen Type III (N-terminal) Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

22734-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 230 publications 230 publications

Immunohistochemistry (IHC)

View 85 publications 85 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:1,000

Immunocytochemistry (ICC/IF)

View 42 publications 42 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Not applicable (N/A)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Dog, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Collagen Type III (N-terminal) Fusion Protein Ag18658 (24-152 aa encoded by BC028178)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.53 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: QQEAVEGGC SHLGQSYADR DVWKPEPCQI CVCDSGSVLC DDIICDDQEL DCPNPEIPFG ECCAVCPQPP TAPTRPPNGQ GPQGPKGDPG PPGIPGRNGD PGIPGQPGSP GSPGPPGICE SCPTGPQNYS (24-152 aa encoded by BC028178)

Target Information

Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Mon Aug 22 00:00:00 EDT 2022

Guanxin V protects against ventricular remodeling after acute myocardial infarction through the interaction of TGF-β1 and Vimentin.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Liang B,Zhang XX,Li R,Gu N

Sat Jan 01 00:00:00 EST 2022

Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.

Frontiers in bioengineering and biotechnology

Dong Y,Lv D,Zhao Z,Xu Z,Hu Z,Tang B

Sat Jul 16 00:00:00 EDT 2022

Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.

Frontiers in bioengineering and biotechnology

Dong Y,Lv D,Zhao Z,Xu Z,Hu Z,Tang B

Sat Jul 16 00:00:00 EDT 2022

Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.

Frontiers in bioengineering and biotechnology

Dong Y,Lv D,Zhao Z,Xu Z,Hu Z,Tang B

Sat Jul 16 00:00:00 EDT 2022

Gaseous signal molecule SO₂ regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Zhao J,Wu Q,Yang T,Nie L,Liu S,Zhou J,Chen J,Jiang Z,Xiao T,Yang J,Chu C

Tue Nov 01 00:00:00 EDT 2022

Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.

Frontiers in pharmacology

Luo Q,Ling Y,Li Y,Qu X,Shi Q,Zheng S,Li Y,Huang Y,Zhou X

Tue Sep 20 00:00:00 EDT 2022

Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.

Biochemical and biophysical research communications

Liu Z,Chen X,Ye T,Wan W,Yu Y,Zhang C,Yang B

Sun Dec 25 00:00:00 EST 2022

Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice.

Parasites & vectors

Huang P,Ma H,Cao Y,Zhan T,Zhang T,Wang X,Zhang Y,Xu J,Xia C

Tue Dec 06 00:00:00 EST 2022

Close Association between Altered Urine-Urothelium Barrier and Tertiary Lymphoid Structure Formation in the Renal Pelvis during Nephritis.

Journal of the American Society of Nephrology : JASN

Ichii O,Hosotani M,Masum MA,Horino T,Otani Y,Namba T,Nakamura T,Hosny Ali EY,Kon Y

Sat Jan 01 00:00:00 EST 2022

Protection of CAPE-pNO₂ Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.

Inflammation

Wan Q,Zhang L,Zhou Q,Han Y,Li Z,Li B

Wed Jun 01 00:00:00 EDT 2022

Protection of CAPE-pNO₂ Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.

Inflammation

Wan Q,Zhang L,Zhou Q,Han Y,Li Z,Li B

Wed Jun 01 00:00:00 EDT 2022

A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.

Biomaterials

Wang S,Yan H,Fang B,Gu C,Guo J,Qiu P,Song N,Xu W,Zhang J,Lin X,Fang X

Wed Jun 01 00:00:00 EDT 2022

ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.

Toxicology and applied pharmacology

Ghafoor H,Chu H,Huang J,Chen M,Wang S,Wang J,Chao J

Sat Jan 15 00:00:00 EST 2022

Guanxin V alleviates acute myocardial infarction by restraining oxidative stress damage, apoptosis, and fibrosis through the TGF-β1 signalling pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Liang B,Zhang XX,Li R,Zhu YC,Tian XJ,Gu N

Wed Jun 01 00:00:00 EDT 2022

Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.

Drug design, development and therapy

Li Y,Li C,Xiong Y,Fang B,Lin X,Huang Q

Wed Jun 15 00:00:00 EDT 2022

The effect of Q-switched 1064-nm dymium-doped yttrium aluminum garnet laser on the skin barrier and collagen synthesis through miR-24-3p.

Lasers in medical science

Yang Z,Duan X,Wang X,Li D,Xu Q,Xiang S,Guo B,He L

Tue Feb 01 00:00:00 EST 2022

COX-2/sEH Dual Inhibitor Alleviates Hepatocyte Senescence in NAFLD Mice by Restoring Autophagy through Sirt1/PI3K/AKT/mTOR.

International journal of molecular sciences

Zhang CY,Tan XH,Yang HH,Jin L,Hong JR,Zhou Y,Huang XT

Wed Jul 27 00:00:00 EDT 2022

Morphological changes of macrophages and their potential contribution to tendon healing.

Colloids and surfaces. B, Biointerfaces

Yang QQ,Zhang L,Zhou YL,Tang JB

Sat Jan 01 00:00:00 EST 2022

KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.

The Journal of investigative dermatology

Zhou Q,Gong J,Bi J,Yang X,Zhang L,Lu C,Li L,Chen M,Cai J,Yang R,Li X,Li Z,Wang X

Fri Jul 01 00:00:00 EDT 2022

QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.

Frontiers in pharmacology

Anwaier G,Xie TT,Pan CS,Li AQ,Yan L,Wang D,Chen FK,Weng DZ,Sun K,Chang X,Fan JY,Han JY,Liu J

Tue Aug 02 00:00:00 EDT 2022

The Apelin-APJ axis alleviates LPS-induced pulmonary fibrosis and endothelial mesenchymal transformation in mice by promoting Angiotensin-Converting Enzyme 2.

Cellular signalling

Wang H,Cong L,Yin X,Zhang N,Zhu M,Sun T,Fan J,Xue F,Fan X,Gong Y

Sat Oct 01 00:00:00 EDT 2022

The Apelin-APJ axis alleviates LPS-induced pulmonary fibrosis and endothelial mesenchymal transformation in mice by promoting Angiotensin-Converting Enzyme 2.

Cellular signalling

Wang H,Cong L,Yin X,Zhang N,Zhu M,Sun T,Fan J,Xue F,Fan X,Gong Y

Sat Oct 01 00:00:00 EDT 2022

Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.

Experimental eye research

Qi X,Luo B,Deng M,Cao J,Hou S,Xie Z,Tong B,Xiong W

Fri Apr 01 00:00:00 EDT 2022

Radix ranunculus temate saponins sensitizes ovarian cancer to Taxol via upregulation of miR-let-7b.

Experimental and therapeutic medicine

You K,Liu Y,Chen L,Ye H,Lin W

Sun May 01 00:00:00 EDT 2022

Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.

Molecules (Basel, Switzerland)

Zhou W,Fu Y,Xu JS

Tue Nov 15 00:00:00 EST 2022

Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.

Journal of cardiovascular pharmacology

Xue K,Chen S,Chai J,Yan W,Zhu X,Dai H,Wang W

Sun May 01 00:00:00 EDT 2022

Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.

Evidence-based complementary and alternative medicine : eCAM

Ma H,Duan X,Zhang R,Li H,Guo Y,Tian Y,Huang M,Chen G,Wang Z,Li L

Thu Dec 21 00:00:00 EST 2023

MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.

Pharmacological research

Zhang Y,Wang Z,Lan D,Zhao J,Wang L,Shao X,Wang D,Wu K,Sun M,Huang X,Yan M,Liang H,Rong X,Diao H,Guo J

Tue Mar 01 00:00:00 EST 2022

Metabotropic glutamate receptor 5 blockade attenuates pathological cardiac remodelling in pulmonary arterial hypertension.

Clinical and experimental pharmacology & physiology

Mprah R,Ma Y,Adzika GK,Ndzie Noah ML,Adekunle AO,Duah M,Adu-Amankwaah J,Wowui PI,Okwuma JD,Qiao W,Wang C

Sun May 01 00:00:00 EDT 2022

C/EBP-β contributes to pig endometrial LE receptivity by targeting cell remodeling genes during implantation.

Reproduction (Cambridge, England)

Sun Y,Yang Y,Jiang Z,Wang F,Han K,Hong L,Cao J,Yu M

Thu Dec 01 00:00:00 EST 2022

Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Mai X,Shang J,Chen Q,Gu S,Hong Y,Zhou J,Zhang M

Tue Nov 01 00:00:00 EDT 2022

Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Mai X,Shang J,Chen Q,Gu S,Hong Y,Zhou J,Zhang M

Tue Nov 01 00:00:00 EDT 2022

Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Mai X,Shang J,Chen Q,Gu S,Hong Y,Zhou J,Zhang M

Tue Nov 01 00:00:00 EDT 2022

Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Mai X,Shang J,Chen Q,Gu S,Hong Y,Zhou J,Zhang M

Tue Nov 01 00:00:00 EDT 2022

Suppression of LMCD1 ameliorates renal fibrosis by blocking the activation of ERK pathway.

Biochimica et biophysica acta. Molecular cell research

Yu R,Tian M,He P,Chen J,Zhao Z,Zhang Y,Zhang B

Fri Apr 01 00:00:00 EDT 2022

Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.

International journal of molecular medicine

Zhang L,Zhang H,Ma J,Wang Y,Pei Z,Ding H

Sun May 01 00:00:00 EDT 2022

Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.

International journal of molecular medicine

Zhang L,Zhang H,Ma J,Wang Y,Pei Z,Ding H

Sun May 01 00:00:00 EDT 2022

Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.

International journal of molecular medicine

Zhang L,Zhang H,Ma J,Wang Y,Pei Z,Ding H

Sun May 01 00:00:00 EDT 2022

Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.

International journal of molecular medicine

Zhang L,Zhang H,Ma J,Wang Y,Pei Z,Ding H

Sun May 01 00:00:00 EDT 2022

Targeting the Akt/PI3K/mTOR signaling pathway for complete eradication of keloid disease by sunitinib.

Apoptosis : an international journal on programmed cell death

Chen Y,Chen C,Fang J,Su K,Yuan Q,Hou H,Xin H,Sun J,Huang C,Li S,Yuan Z,Luo S

Thu Dec 01 00:00:00 EST 2022

Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.

European journal of pharmacology

Shu J,Hu L,Wu Y,Chen L,Huang K,Wang Z,Liang M

Tue Mar 15 00:00:00 EDT 2022

Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.

Journal of cosmetic dermatology

Li Q,Liu L,Jiang S,Xu Z,Lin S,Tong Y,Wang P

Tue Mar 01 00:00:00 EST 2022

Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.

Neuropathology : official journal of the Japanese Society of Neuropathology

Wakamatsu K,Chiba Y,Murakami R,Matsumoto K,Miyai Y,Kawauchi M,Yanase K,Uemura N,Ueno M

Fri Apr 01 00:00:00 EDT 2022

Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.

Neuropathology : official journal of the Japanese Society of Neuropathology

Wakamatsu K,Chiba Y,Murakami R,Matsumoto K,Miyai Y,Kawauchi M,Yanase K,Uemura N,Ueno M

Fri Apr 01 00:00:00 EDT 2022

Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.

International journal of endocrinology

Peng M,Liu H,Ji Q,Ma P,Niu Y,Ning S,Sun H,Pang X,Yang Y,Zhang Y,Han J,Hao G

Sat Oct 15 00:00:00 EDT 2022

Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.

International journal of endocrinology

Peng M,Liu H,Ji Q,Ma P,Niu Y,Ning S,Sun H,Pang X,Yang Y,Zhang Y,Han J,Hao G

Sat Oct 15 00:00:00 EDT 2022

Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.

Chinese medicine

Qi W,Li X,Ren Y,Liu X,Fu H,Wang X,Li X,Xiong J,Zheng Q,Cai D,Liang F

Tue May 17 00:00:00 EDT 2022

Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway.

Journal of the American Heart Association

Li L,Gan H

Tue Sep 20 00:00:00 EDT 2022

Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway.

Journal of the American Heart Association

Li L,Gan H

Tue Sep 20 00:00:00 EDT 2022

Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway.

Journal of the American Heart Association

Li L,Gan H

Tue Sep 20 00:00:00 EDT 2022

Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.

Frontiers in physiology

Thant L,Kaku M,Kakihara Y,Mizukoshi M,Kitami M,Arai M,Kitami K,Kobayashi D,Yoshida Y,Maeda T,Saito I,Uoshima K,Saeki M

Sat Jul 16 00:00:00 EDT 2022

A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.

Acta biomaterialia

Zhao Y,Xue P,Lin G,Tong M,Yang J,Zhang Y,Ran K,Zhuge D,Yao Q,Xu H

Fri Apr 15 00:00:00 EDT 2022

Substitution of SERCA2 Cys⁶⁷⁴ aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts.

Biochemical pharmacology

Huang X,Lin X,Wang L,Xie Y,Que Y,Li S,Hu P,Tong X

Thu Sep 01 00:00:00 EDT 2022

LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.

The Journal of investigative dermatology

Chen L,Su Y,Yin B,Li S,Cheng X,He Y,Jia C

Thu Sep 01 00:00:00 EDT 2022

Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells.

Experimental & molecular medicine

Fan LL,Du R,Liu JS,Jin JY,Wang CY,Dong Y,He WX,Yan RQ,Xiang R

Sun May 01 00:00:00 EDT 2022

Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression.

Bioengineered

Li J,Li Z,Wang S,Bi J,Huo R

Fri Apr 01 00:00:00 EDT 2022

The Role of Verteporfin in Prevention of Periprosthetic Capsular Fibrosis: An Experimental Study.

Aesthetic surgery journal

Yi Z,Zeng J,Chen Z,Chen L,Lu HB,Zhang Q,Yang X,Qi Z

Mon Jun 20 00:00:00 EDT 2022

Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.

International immunopharmacology

Song Z,Wang L,Cao Y,Liu Z,Zhang M,Zhang Z,Jiang S,Fan R,Hao T,Yang R,Wang B,Guan Z,Zhu L,Liu Z,Zhang S,Zhao L,Xu Z,Xu H,Dai G

Fri Apr 01 00:00:00 EDT 2022

Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.

International immunopharmacology

Song Z,Wang L,Cao Y,Liu Z,Zhang M,Zhang Z,Jiang S,Fan R,Hao T,Yang R,Wang B,Guan Z,Zhu L,Liu Z,Zhang S,Zhao L,Xu Z,Xu H,Dai G

Fri Apr 01 00:00:00 EDT 2022

Collagen and elastic fiber remodeling in the pregnant mouse myometrium†.

Biology of reproduction

Ouellette A,Mahendroo M,Nallasamy S

Mon Sep 12 00:00:00 EDT 2022

Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.

Biomaterials advances

Li H,You S,Yang X,Liu S,Hu L

Tue Mar 01 00:00:00 EST 2022

Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.

International journal of molecular sciences

Chen YC,Chang HN,Pang JS,Lin LP,Chen JM,Yu TY,Tsai WC

Sun Aug 07 00:00:00 EDT 2022

TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation.

Clinical and translational medicine

Baik JE,Park HJ,Kataru RP,Savetsky IL,Ly CL,Shin J,Encarnacion EM,Cavali MR,Klang MG,Riedel E,Coriddi M,Dayan JH,Mehrara BJ

Wed Jun 01 00:00:00 EDT 2022

Cell contractility and focal adhesion kinase control circumferential arterial stiffness.

Vascular biology (Bristol, England)

Roberts E,Xu T,Assoian RK

Tue Nov 01 00:00:00 EDT 2022

Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.

Journal of Zhejiang University. Science. B

Li M,Su Y,Gao X,Yu J,Wang Z,Wang X

Tue Mar 15 00:00:00 EDT 2022

BMP-7 Upregulates Id2 Through the MAPK Signaling Pathway to Improve Diabetic Tubulointerstitial Fibrosis and the Intervention of Oxymatrine.

Frontiers in pharmacology

Xiao Y,Liang D,Li Z,Feng Z,Yuan Z,Zhang F,Wang Y,Zhou Y,Shi M,Liu L,Xiao Y,Guo B

Sat Jul 16 00:00:00 EDT 2022

Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.

Frontiers in pharmacology

He J,Xu D,Wang L,Yu X

Thu Feb 02 00:00:00 EST 2023

Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.

Frontiers in pharmacology

He J,Xu D,Wang L,Yu X

Thu Feb 02 00:00:00 EST 2023

Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.

Frontiers in pharmacology

He J,Xu D,Wang L,Yu X

Thu Feb 02 00:00:00 EST 2023

Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.

Frontiers in pharmacology

He J,Xu D,Wang L,Yu X

Thu Feb 02 00:00:00 EST 2023

A Novel miRNA From Egg-Derived Exosomes of Schistosoma japonicum Promotes Liver Fibrosis in Murine Schistosomiasis.

Frontiers in immunology

Wang Y,Gong W,Zhou H,Hu Y,Wang L,Shen Y,Yu G,Cao J

Thu May 19 00:00:00 EDT 2022

Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts.

Bioengineered

Li J,Zou Y,Wang S,Guo S,Huang Z,Huo R

Sat Jan 01 00:00:00 EST 2022

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

International journal of molecular sciences

Dahlke E,Engmann T,Anan Y,Häsler R,Solinas G,Theilig F

Mon Sep 05 00:00:00 EDT 2022

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

International journal of molecular sciences

Dahlke E,Engmann T,Anan Y,Häsler R,Solinas G,Theilig F

Mon Sep 05 00:00:00 EDT 2022

Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.

Free radical research

Zheng J,Wang Y,Wang Z,Chen W,Luo M,Zhang C,Wang Y,Chen L,Wu F,Yang W,Yang Z,Wang Y,Shi C

Wed Nov 30 00:00:00 EST 2022

Endoplasmic reticulum-to-Golgi trafficking of procollagen III via conventional vesicular and tubular carriers.

Molecular biology of the cell

Hirata Y,Matsui Y,Wada I,Hosokawa N

Tue Mar 01 00:00:00 EST 2022

Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.

Cardiovascular research

Yao Y,Song Q,Hu C,Da X,Yu Y,He Z,Xu C,Chen Q,Wang QK

Fri Jan 07 00:00:00 EST 2022

Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.

Frontiers in cardiovascular medicine

Wang W,He Q,Li C,Zhuang C,Zhang H,Wang Q,Fan X,Qi M,Sun R,Yu J

Thu Nov 17 00:00:00 EST 2022

Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.

Journal of cardiovascular translational research

Guo J,Chen LW,Huang ZQ,Guo JS,Li H,Shan Y,Chen ZR,Yan YM,Zhu JN,Guo HM,Fang XH,Shan ZX

Wed Jun 01 00:00:00 EDT 2022

NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy.

Frontiers in pharmacology

Zhang D,Li Y,Wang W,Lang X,Zhang Y,Zhao Q,Yan J,Zhang Y

Fri Oct 14 00:00:00 EDT 2022

Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.

Frontiers in pharmacology

Lin X,Wei Y,Li Y,Xiong Y,Fang B,Li C,Huang Q,Huang R,Wei J

Sat Apr 02 00:00:00 EDT 2022

Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing.

Macromolecular bioscience

Chang P,Li S,Sun Q,Guo K,Wang H,Li S,Zhang L,Xie Y,Zheng X,Liu Y

Tue Feb 01 00:00:00 EST 2022

In situ hydrogel capturing nitric oxide microbubbles accelerates the healing of diabetic foot.

Journal of controlled release : official journal of the Controlled Release Society

Zhao Y,Luo L,Huang L,Zhang Y,Tong M,Pan H,Shangguan J,Yao Q,Xu S,Xu H

Sat Oct 01 00:00:00 EDT 2022

Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.

Frontiers in cardiovascular medicine

Rui H,Zhao F,Yuhua L,Hong J

Tue Mar 21 00:00:00 EDT 2023

Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner.

Translational research : the journal of laboratory and clinical medicine

Su M,Li W,Yuan Y,Liu S,Liang C,Liu HE,Zhang R,Liu Y,Sun LI,Wei Y,Li C,Han X,Hao H,Zhao X,Luo Y,Yan S,Pan Z,Li Y

Sat Oct 01 00:00:00 EDT 2022

Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway.

Pharmaceutical biology

Wu C,Chen RL,Wang Y,Wu WY,Li G

Thu Dec 01 00:00:00 EST 2022

Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1.

Frontiers in pharmacology

Liang D,Li Z,Feng Z,Yuan Z,Dai Y,Wu X,Zhang F,Wang Y,Zhou Y,Liu L,Shi M,Xiao Y,Guo B

Sat Jul 16 00:00:00 EDT 2022

The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.

Evidence-based complementary and alternative medicine : eCAM

Zhang Y,Wang D,Wu K,Shao X,Diao H,Wang Z,Sun M,Huang X,Li Y,Tang X,Yan M,Guo J

Sat Jul 16 00:00:00 EDT 2022

QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.

Pharmaceutical biology

Lv S,Zhang W,Yuan P,Lu C,Dong J,Zhang J

Thu Dec 01 00:00:00 EST 2022

Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Xu Y,Wang X,Han D,Wang J,Luo Z,Jin T,Shi C,Zhou X,Lin L,Shan J

Wed Jul 20 00:00:00 EDT 2022

Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.

Computational and mathematical methods in medicine

Gao L,Kan C,Chen X,Xu S,Shi K

Tue Jun 21 00:00:00 EDT 2022

The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.

Biochimica et biophysica acta. Molecular basis of disease

Wang G,Duan J,Pu G,Ye C,Li Y,Xiu W,Xu J,Liu B,Zhu Y,Wang C

Mon Aug 01 00:00:00 EDT 2022

STAMP2 Attenuates Cardiac Dysfunction and Insulin Resistance in Diabetic Cardiomyopathy via NMRAL1-Mediated NF-κB Inhibition in Type 2 Diabetic Rats.

Diabetes, metabolic syndrome and obesity : targets and therapy

Gao Z,Ti Y,Lu B,Song FQ,Zhang L,Hu BA,Xie JY,Zhang W,Han L,Zhong M

Tue Nov 01 00:00:00 EDT 2022

Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats.

Disease markers

Ge C,Zhao Y,Liang Y,He Y

Fri Jul 22 00:00:00 EDT 2022

AGEs-RAGE axis mediates myocardial fibrosis via activation of cardiac fibroblasts induced by autophagy in heart failure.

Experimental physiology

Liang B,Zhou Z,Yang Z,Liu J,Zhang L,He J,Li H,Huang Y,Yang Q,Xian S,Wang L

Mon Aug 01 00:00:00 EDT 2022

Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages.

Cells

Shi L,Jiang Z,Li J,Lin H,Xu B,Liao X,Fu Z,Ao H,Guo G,Liu M

Fri Dec 16 00:00:00 EST 2022

Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages.

Cells

Shi L,Jiang Z,Li J,Lin H,Xu B,Liao X,Fu Z,Ao H,Guo G,Liu M

Fri Dec 16 00:00:00 EST 2022

The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.

PloS one

Liu C,Wang C,Yang F,Lu Y,Du P,Hu K,Yin X,Zhao P,Lu G

Wed Apr 13 00:00:00 EDT 2022

Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.

Journal of translational medicine

Hao H,Yan S,Zhao X,Han X,Fang N,Zhang Y,Dai C,Li W,Yu H,Gao Y,Wang D,Gao Q,Duan Y,Yuan Y,Li Y

Mon Sep 05 00:00:00 EDT 2022

Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.

Frontiers in medicine

Wang D,Yin L,Chen R,Tan W,Liang L,Xiang J,Zhang H,Zhou X,Deng H,Guo B,Wang Y

Sat Feb 11 00:00:00 EST 2023

Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.

Drug design, development and therapy

Hu H,Mao G,Zheng J,Guo F

Fri Dec 23 00:00:00 EST 2022

Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.

Frontiers in pharmacology

Gu YH,Ren KW,Wang Y,Wang SH,Yu XH,Xu LW,Li HH,Bi HL

Fri Nov 18 00:00:00 EST 2022

Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.

Oxidative medicine and cellular longevity

Zhang M,Lin D,Luo C,Wei P,Cui K,Chen Z

Fri Mar 18 00:00:00 EDT 2022

Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Xie L,Wang T,Lin S,Lu Z,Wang Y,Shen Z,Cheng Y,Shen A,Peng J,Chu J

Tue Feb 01 00:00:00 EST 2022

Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Xie L,Wang T,Lin S,Lu Z,Wang Y,Shen Z,Cheng Y,Shen A,Peng J,Chu J

Tue Feb 01 00:00:00 EST 2022

Spatio-Temporal Changes of Extracellular Matrix (ECM) Stiffness in the Development of the Leech Hirudo verbana.

International journal of molecular sciences

Pulze L,Baranzini N,Congiu T,Acquati F,Grimaldi A

Thu Dec 15 00:00:00 EST 2022

Deletion of fibroblast activation protein provides atheroprotection.

Cardiovascular research

Stein S,Weber J,Nusser-Stein S,Pahla J,Zhang HE,Mohammed SA,Oppi S,Gaul DS,Paneni F,Tailleux A,Staels B,von Meyenn F,Ruschitzka F,Gorrell MD,Lüscher TF,Matter CM

Sun Mar 21 00:00:00 EDT 2021

Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.

Oxidative medicine and cellular longevity

Zhang M,Luo C,Lin D,Cui K,Chen Z,Liu J

Fri Nov 12 00:00:00 EST 2021

Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.

Molecular medicine reports

Wang Y,Chang T,Wu T,Ye W,Wang Y,Dou G,Du H,Hui Y,Guo C

Sat May 01 00:00:00 EDT 2021

Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.

Molecular medicine reports

Wang Y,Chang T,Wu T,Ye W,Wang Y,Dou G,Du H,Hui Y,Guo C

Sat May 01 00:00:00 EDT 2021

FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model.

Evidence-based complementary and alternative medicine : eCAM

Wang L,Wu H,Deng Y,Zhang S,Wei Q,Yang Q,Piao S,Bei W,Rong X,Guo J

Wed Apr 27 00:00:00 EDT 2022

IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.

The Journal of surgical research

Cheng S,Lv R,Xu J,Hirman AR,Du L

Wed Sep 01 00:00:00 EDT 2021

The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs.

Immunology and cell biology

Parkinson JE,Pearson S,Rückerl D,Allen JE,Sutherland TE

Thu Jul 01 00:00:00 EDT 2021

Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.

International journal of pharmaceutics

Wang X,Wan W,Lu J,Quan G,Pan X,Liu P

Wed Dec 15 00:00:00 EST 2021

Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Wang Z,Feng F,He H,Wu Q,Gu C,Hrovat J,Peng W,Xu Y,Han D,Yang P,Zhou X,Li J,Shan J

Sun Aug 01 00:00:00 EDT 2021

Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.

Journal of cellular and molecular medicine

Nie C,Zou R,Pan S,A R,Gao Y,Yang H,Bai J,Xi S,Wang X,Hong X,Yang W

Wed Sep 01 00:00:00 EDT 2021

Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.

Journal of ginseng research

Lu ML,Wang J,Sun Y,Li C,Sun TR,Hou XW,Wang HX

Mon Nov 01 00:00:00 EDT 2021

HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.

Journal of experimental & clinical cancer research : CR

Cao Z,Cheng Y,Wang J,Liu Y,Yang R,Jiang W,Li H,Zhang X

Thu Apr 01 00:00:00 EDT 2021

Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication.

Frontiers in cell and developmental biology

Pan C,Fang Q,Liu P,Ma D,Cao S,Zhang L,Chen Q,Hu T,Wang J

Fri Nov 05 00:00:00 EDT 2021

Frontiers in cell and developmental biology

Pan C,Fang Q,Liu P,Ma D,Cao S,Zhang L,Chen Q,Hu T,Wang J

Fri Nov 05 00:00:00 EDT 2021

Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.

Experimental and therapeutic medicine

Liang L,Li S,Liu H,Mao Y,Liu L,Zhang X,Peng W,Xiao Y,Zhang F,Shi M,Wang Y,Guo B

Mon Nov 01 00:00:00 EDT 2021

Dickkopf 3: a Novel Target Gene of miR-25-3p in Promoting Fibrosis-Related Gene Expression in Myocardial Fibrosis.

Journal of cardiovascular translational research

Zeng N,Wen YH,Pan R,Yang J,Yan YM,Zhao AZ,Zhu JN,Fang XH,Shan ZX

Wed Dec 01 00:00:00 EST 2021

Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.

Journal of cardiovascular pharmacology

Wang R,Peng L,Lv D,Shang F,Yan J,Li G,Li D,Ouyang J,Yang J

Mon Feb 01 00:00:00 EST 2021

Pathological Alternations of Mediastinal Fat-Associated Lymphoid Cluster and Lung in a Streptozotocin-Induced Diabetic Mouse Model.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

Elewa YHA,Ichii O,Nakamura T,Kon Y

Mon Feb 01 00:00:00 EST 2021

LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.

Frontiers in pharmacology

Dai H,Zhao N,Liu H,Zheng Y,Zhao L

Fri May 28 00:00:00 EDT 2021

Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.

Journal of materials chemistry. B

Pan H,Shi C,Yang R,Xi G,Lu C,Yang X,Chen J,Wang X,Chen L,Pan J

Wed May 19 00:00:00 EDT 2021

Changes in aortic collagen in β-aminopropionitrile-induced acute aortic dissection.

Annals of translational medicine

Zhou H,Ren Y,Xiao J,He J,Zhang Y,Qiu Z,Huang Q,Hu Y,Chen L

Fri Oct 01 00:00:00 EDT 2021

Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways.

Medical science monitor : international medical journal of experimental and clinical research

Zhou J,Zhang X,Wan L,Yu J,Li T,Lu Z,Fang N,Sun L,Ye F

Wed Apr 14 00:00:00 EDT 2021

Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.

Clinical science (London, England : 1979)

Ge C,Cheng Y,Fan Y,He Y

Fri Jun 11 00:00:00 EDT 2021

M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.

International immunopharmacology

Zhou M,Li B,Liu C,Hu M,Tang J,Min J,Cheng J,Hong L

Wed Dec 01 00:00:00 EST 2021

Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.

Frontiers in cardiovascular medicine

Zhang L,Li C,Yang L,Adzika GK,Machuki JO,Shi M,Sun Q,Sun H

Tue Jul 06 00:00:00 EDT 2021

Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway.

Theranostics

Lee TL,Lai TC,Lin SR,Lin SW,Chen YC,Pu CM,Lee IT,Tsai JS,Lee CW,Chen YL

Tue Jul 27 00:00:00 EDT 2021

Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway.

Theranostics

Lee TL,Lai TC,Lin SR,Lin SW,Chen YC,Pu CM,Lee IT,Tsai JS,Lee CW,Chen YL

Tue Jul 27 00:00:00 EDT 2021

Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.

Molecular medicine reports

Lv W,Wu M,Ren Y,Luo X,Hu W,Zhang Q,Wu Y

Fri Jan 01 00:00:00 EST 2021

Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.

Molecular medicine reports

Lv W,Wu M,Ren Y,Luo X,Hu W,Zhang Q,Wu Y

Fri Jan 01 00:00:00 EST 2021

Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.

International journal of molecular sciences

Ma Y,Kuang Y,Bo W,Liang Q,Zhu W,Cai M,Tian Z

Mon Nov 15 00:00:00 EST 2021

Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.

Frontiers in cardiovascular medicine

Liu J,Ji XX,Fu Y,Zhang WC,Ji HF,Liu JW,Cheng XS,Dong YF

Thu May 13 00:00:00 EDT 2021

Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.

Journal of ethnopharmacology

Peng M,Yang M,Lu Y,Lin S,Gao H,Xie L,Huang B,Chen D,Shen A,Shen Z,Peng J,Chu J

Thu Jul 15 00:00:00 EDT 2021

Qingda granule attenuates cardiac fibrosis via suppression of the TGF-β1/Smad2/3 signaling pathway in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Chen X,Long L,Cheng Y,Chu J,Shen Z,Liu L,Li J,Xie Q,Liu H,Wu M,Chen Y,Peng J,Shen A

Sat May 01 00:00:00 EDT 2021

Qingda granule attenuates cardiac fibrosis via suppression of the TGF-β1/Smad2/3 signaling pathway in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Chen X,Long L,Cheng Y,Chu J,Shen Z,Liu L,Li J,Xie Q,Liu H,Wu M,Chen Y,Peng J,Shen A

Sat May 01 00:00:00 EDT 2021

Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.

Theranostics

Zhao H,Yang H,Geng C,Chen Y,Tang Y,Li Z,Pang J,Shu T,Nie Y,Liu Y,Jia K,Wang J

Wed Jul 28 00:00:00 EDT 2021

Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression.

Cancers

Kang SH,Oh SY,Lee HJ,Kwon TG,Kim JW,Lee ST,Choi SY,Hong SH

Sat Feb 06 00:00:00 EST 2021

Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression.

Cancers

Kang SH,Oh SY,Lee HJ,Kwon TG,Kim JW,Lee ST,Choi SY,Hong SH

Sat Feb 06 00:00:00 EST 2021

Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.

Experimental and therapeutic medicine

Meng X,Gao X,Chen X,Yu J

Mon Mar 01 00:00:00 EST 2021

PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.

Frontiers in cardiovascular medicine

Li J,Wang C,Wang W,Liu L,Zhang Q,Zhang J,Wang B,Wang S,Hou L,Gao C,Yu X,Sun L

Fri Apr 02 00:00:00 EDT 2021

Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.

Pharmaceutical biology

Cui Y,Wang Y,Liu G

Wed Dec 01 00:00:00 EST 2021

Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.

Journal of cellular and molecular medicine

Sun Y,Zhang L,Lu B,Wen J,Wang M,Zhang S,Li Q,Shu F,Lu F,Liu N,Peng S,Zhao Y,Dong S,Lu F,Zhang W,Wang Y

Fri Oct 01 00:00:00 EDT 2021

The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy.

Frontiers in pharmacology

Ding Q,Wei Q,Sheng G,Wang S,Jing S,Ma T,Zhang R,Wang T,Li W,Tang X,Wu H,Liu C

Tue Jan 04 00:00:00 EST 2022

Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats.

Life sciences

Tang S,Huang Z,Jiang J,Gao J,Zhao C,Tai Y,Ma X,Zhang L,Ye Y,Gan C,Su W,Jia X,Liu R,Wu H,Tang C

Sat May 01 00:00:00 EDT 2021

Epicardium-Derived Tbx18⁺ CDCs Transplantation Improve Heart Function in Infarcted Mice.

Frontiers in cardiovascular medicine

Guo Z,Geng M,Qin L,Hao B,Liao S

Wed Feb 16 00:00:00 EST 2022

Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction.

Stem cell research & therapy

Cao D,Wang Y,Zhang Y,Zhang Y,Huang Q,Yin Z,Cai G,Chen X,Sun X

Wed Mar 10 00:00:00 EST 2021

Mesenchymal Stem Cell-Derived Exosomes Ameliorate Dermal Fibrosis in a Murine Model of Bleomycin-Induced Scleroderma.

Stem cells and development

Li M,Zhang HP,Wang XY,Chen ZG,Lin XF,Zhu W

Fri Oct 01 00:00:00 EDT 2021

Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.

Pharmaceutical biology

Ke S,Wu L,Wang M,Liu D,Shi G,Zhu J,Qian X

Wed Dec 01 00:00:00 EST 2021

Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats.

Pharmaceutical biology

Lu B,Xie J,Fu D,Chen X,Zhao M,Gui M,Yao L,Zhou X,Li J

Wed Dec 01 00:00:00 EST 2021

Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats.

Pharmaceutical biology

Lu B,Xie J,Fu D,Chen X,Zhao M,Gui M,Yao L,Zhou X,Li J

Wed Dec 01 00:00:00 EST 2021

ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.

The EMBO journal

Zuo S,Wang B,Liu J,Kong D,Cui H,Jia Y,Wang C,Xu X,Chen G,Wang Y,Yang L,Zhang K,Ai D,Du J,Shen Y,Yu Y

Mon Aug 16 00:00:00 EDT 2021

Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.

Journal of cellular and molecular medicine

Wang Q,Ma E,Wo D,Chen J,He J,Peng J,Zhu W,Ren DN

Wed Dec 01 00:00:00 EST 2021

Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.

Journal of agricultural and food chemistry

Wang X,Gao Y,Wang L,Yang D,Bu W,Gou L,Huang J,Duan X,Pan Y,Cao S,Gao Z,Cheng C,Feng Z,Xie J,Yao R

Wed Mar 10 00:00:00 EST 2021

Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.

Journal of agricultural and food chemistry

Wang X,Gao Y,Wang L,Yang D,Bu W,Gou L,Huang J,Duan X,Pan Y,Cao S,Gao Z,Cheng C,Feng Z,Xie J,Yao R

Wed Mar 10 00:00:00 EST 2021

Tenogenic adipose-derived stem cell sheets with nanoyarn scaffolds for tendon regeneration.

Materials science & engineering. C, Materials for biological applications

Chen S,Wang J,Chen Y,Mo X,Fan C

Mon Feb 01 00:00:00 EST 2021

Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.

Burns : journal of the International Society for Burn Injuries

Lv W,Ren Y,Wu M,Luo X,Yu J,Zhang Q,Wu Y

Wed Sep 01 00:00:00 EDT 2021

Canine Mesenchymal Stromal Cell-Mediated Bone Regeneration is Enhanced in the Presence of Sub-Therapeutic Concentrations of BMP-2 in a Murine Calvarial Defect Model.

Frontiers in bioengineering and biotechnology

Dobson LK,Zeitouni S,McNeill EP,Bearden RN,Gregory CA,Saunders WB

Sat Nov 20 00:00:00 EST 2021

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.

Toxicology

An R,Wang X,Yang L,Zhang J,Wang N,Xu F,Hou Y,Zhang H,Zhang L

Mon Feb 15 00:00:00 EST 2021

Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.

Experimental and therapeutic medicine

Xu Y,Peng W,Han D,Feng F,Wang Z,Gu C,Zhou X,Wu Q

Mon Nov 01 00:00:00 EDT 2021

Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.

Experimental and therapeutic medicine

Xu Y,Peng W,Han D,Feng F,Wang Z,Gu C,Zhou X,Wu Q

Mon Nov 01 00:00:00 EDT 2021

Microsphere-Embedded Hydrogel Sustained-Release System to Inhibit Postoperative Epidural Fibrosis.

ACS applied bio materials

Wang S,Shi K,Lu J,Sun W,Han Q,Che L,Zhang D

Mon Jun 21 00:00:00 EDT 2021

Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.

Frontiers in molecular biosciences

Jiao W,Bai M,Yin H,Liu J,Sun J,Su X,Zeng H,Wen J

Tue Sep 21 00:00:00 EDT 2021

Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway.

Frontiers in pharmacology

Zhang X,Wang L,Guo R,Xiao J,Liu X,Dong M,Luan X,Ji X,Lu H

Sat Oct 30 00:00:00 EDT 2021

SAIL: a new conserved anti-fibrotic lncRNA in the heart.

Basic research in cardiology

Luo S,Zhang M,Wu H,Ding X,Li D,Dong X,Hu X,Su S,Shang W,Wu J,Xiao H,Yang W,Zhang Q,Zhang J,Lu Y,Pan Z

Sat Mar 06 00:00:00 EST 2021

Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway.

Peptides

Wang Q,Liu AD,Li TS,Tang Q,Wang XC,Chen XB

Fri Oct 01 00:00:00 EDT 2021

Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.

Journal of burn care & research : official publication of the American Burn Association

Li Q,Fang L,Chen J,Zhou S,Zhou K,Cheng F,Cen Y,Qing Y,Wu J

Wed Nov 24 00:00:00 EST 2021

Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.

Medical science monitor : international medical journal of experimental and clinical research

Han D,Xu Y,Peng WP,Feng F,Wang Z,Gu C,Zhou X

Fri Mar 12 00:00:00 EST 2021

SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.

Acta pharmaceutica Sinica. B

Long F,Yang D,Wang J,Wang Q,Ni T,Wei G,Zhu Y,Liu X

Sat May 01 00:00:00 EDT 2021

Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.

Mediators of inflammation

Liu L,Luo F,Lei K

Fri Jan 07 00:00:00 EST 2022

Tryptophan catabolism is dysregulated in leiomyomas.

Fertility and sterility

Chuang TD,Quintanilla D,Boos D,Khorram O

Fri Oct 01 00:00:00 EDT 2021

Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling.

Cell death discovery

Yin P,Li D,Zhao Q,Cai M,Wu Z,Shi Y,Su L

Tue Dec 14 00:00:00 EST 2021

A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.

Toxicology letters

Liao J,Zhang Z,Yuan Q,Liu Q,Kuang J,Fang Y,Hu X

Fri Jan 01 00:00:00 EST 2021

Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.

Clinical and experimental pharmacology & physiology

Zhao B,Li S,Guo Z,Chen Z,Zhang X,Xu C,Chen J,Wei C

Mon Mar 01 00:00:00 EST 2021

Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.

International immunopharmacology

Chen C,Gu J,Wang J,Wu Y,Yang A,Chen T,Zhou T,Liu Z

Fri Jan 01 00:00:00 EST 2021

Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.

Molecular medicine reports

Liu YS,Yang Q,Li S,Luo L,Liu HY,Li XY,Gao ZN

Mon Feb 01 00:00:00 EST 2021

Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.

Molecular medicine reports

Liu YS,Yang Q,Li S,Luo L,Liu HY,Li XY,Gao ZN

Mon Feb 01 00:00:00 EST 2021

Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.

Molecular therapy. Nucleic acids

Zeng N,Huang YQ,Yan YM,Hu ZQ,Zhang Z,Feng JX,Guo JS,Zhu JN,Fu YH,Wang XP,Zhang MZ,Duan JZ,Zheng XL,Xu JD,Shan ZX

Fri Dec 03 00:00:00 EST 2021

Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.

Molecular medicine reports

Xu P,Yi Y,Luo Y,Liu Z,Xu Y,Cai J,Zeng Z,Liu A

Wed Dec 01 00:00:00 EST 2021

Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.

Molecular medicine reports

Xu P,Yi Y,Luo Y,Liu Z,Xu Y,Cai J,Zeng Z,Liu A

Wed Dec 01 00:00:00 EST 2021

Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β-Smad3 Pathway.

Frontiers in pharmacology

Wang Y,Yu K,Zhao C,Zhou L,Cheng J,Wang DW,Zhao C

Sat Aug 14 00:00:00 EDT 2021

CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway.

Stem cells international

Ye Y,Ke Y,Liu L,Xiao T,Yu J

Sun Nov 05 00:00:00 EDT 2023

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Aging

Liu H,Yan R,Liang L,Zhang H,Xiang J,Liu L,Zhang X,Mao Y,Peng W,Xiao Y,Zhang F,Zhou Y,Shi M,Wang Y,Guo B

Wed Feb 17 00:00:00 EST 2021

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Aging

Liu H,Yan R,Liang L,Zhang H,Xiang J,Liu L,Zhang X,Mao Y,Peng W,Xiao Y,Zhang F,Zhou Y,Shi M,Wang Y,Guo B

Wed Feb 17 00:00:00 EST 2021

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Aging

Liu H,Yan R,Liang L,Zhang H,Xiang J,Liu L,Zhang X,Mao Y,Peng W,Xiao Y,Zhang F,Zhou Y,Shi M,Wang Y,Guo B

Wed Feb 17 00:00:00 EST 2021

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Aging

Liu H,Yan R,Liang L,Zhang H,Xiang J,Liu L,Zhang X,Mao Y,Peng W,Xiao Y,Zhang F,Zhou Y,Shi M,Wang Y,Guo B

Wed Feb 17 00:00:00 EST 2021

Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yun W,Qian L,Yuan R,Xu H

Thu Jul 01 00:00:00 EDT 2021

Effect of different exercise training intensities on age-related cardiac damage in male mice.

Aging

Pei Z,Yang C,Guo Y,Dong M,Wang F

Tue Sep 14 00:00:00 EDT 2021

COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.

The FEBS journal

Zhang CY,Duan JX,Yang HH,Sun CC,Zhong WJ,Tao JH,Guan XX,Jiang HL,Hammock BD,Hwang SH,Zhou Y,Guan CX

Wed Apr 01 00:00:00 EDT 2020

The role of Hrd1 in ultraviolet (UV) radiation induced photoaging.

Aging

Jin Y,Cheng X,Huang X,Ding F,Lee SR,Wang F,Lu X,Su D,Chen B

Mon Nov 09 00:00:00 EST 2020

Splenectomy enhances the Ly6C^low phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis.

International immunopharmacology

Zheng Z,Wang H,Li L,Zhang S,Zhang C,Zhang H,Ji F,Liu X,Zhu K,Kong G,Li Z

Tue Sep 01 00:00:00 EDT 2020

Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system.

International journal of pharmaceutics

He J,Chen H,Zhou W,Chen M,Yao Y,Zhang Z,Tan N

Tue Jun 30 00:00:00 EDT 2020

Construction and performance evaluation of Hep/silk-PLCL composite nanofiber small-caliber artificial blood vessel graft.

Biomaterials

Kuang H,Wang Y,Shi Y,Yao W,He X,Liu X,Mo X,Lu S,Zhang P

Sun Nov 01 00:00:00 EDT 2020

MicroRNA-21-3p Engineered Umbilical Cord Stem Cell-Derived Exosomes Inhibit Tendon Adhesion.

Journal of inflammation research

Yao Z,Li J,Wang X,Peng S,Ning J,Qian Y,Fan C

Sat Apr 16 00:00:00 EDT 2022

Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring.

American journal of physiology. Heart and circulatory physiology

Chuang TD,Ansari A,Yu C,Sakurai R,Harb A,Liu J,Khorram O,Rehan VK

Tue Sep 01 00:00:00 EDT 2020

Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring.

American journal of physiology. Heart and circulatory physiology

Chuang TD,Ansari A,Yu C,Sakurai R,Harb A,Liu J,Khorram O,Rehan VK

Tue Sep 01 00:00:00 EDT 2020

Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.

International journal of molecular medicine

Du Y,Xiao H,Wan J,Wang X,Li T,Zheng S,Feng J,Ye Q,Li J,Li G,Fan Z

Sat Aug 01 00:00:00 EDT 2020

Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.

Digestive diseases and sciences

Li J,Liu L,Zhao Q,Chen M

Wed Jul 01 00:00:00 EDT 2020

Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.

The Journal of pharmacy and pharmacology

Fu S,Li Y,Wu Y,Yue Y,Yang D

Sat Feb 01 00:00:00 EST 2020

Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.

The Annals of thoracic surgery

Ma N,Lu R,Zhao D,Jiang Z,Tang M,Bao C,Mei J

Wed Jan 01 00:00:00 EST 2020

KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.

BMJ open diabetes research & care

Yang X,Yang R,Chen M,Zhou Q,Zheng Y,Lu C,Bi J,Sun W,Huang T,Li L,Gong J,Li X,Hui Q,Wang X

Fri May 01 00:00:00 EDT 2020

KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.

BMJ open diabetes research & care

Yang X,Yang R,Chen M,Zhou Q,Zheng Y,Lu C,Bi J,Sun W,Huang T,Li L,Gong J,Li X,Hui Q,Wang X

Fri May 01 00:00:00 EDT 2020

Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling.

Journal of ethnopharmacology

Li J,Ma J,Tian Y,Zhao P,Liu X,Dong H,Zheng W,Feng S,Zhang L,Wu M,Zhu L,Liu S,Zhao D

Wed Jul 15 00:00:00 EDT 2020

Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Su C,Wang Q,Luo H,Jiao W,Tang J,Li L,Tian L,Chen X,Liu B,Yu X,Li S,Guo S,Wang W

Wed Jul 01 00:00:00 EDT 2020

Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.

PLoS pathogens

Kong H,He J,Guo S,Song Q,Xiang D,Tao R,Yu H,Chen G,Huang Z,Ning Q,Huang J

Thu Oct 01 00:00:00 EDT 2020

Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.

International journal of molecular medicine

Wang X,Lin L,Chai X,Wu Y,Li Y,Liu X

Wed Jan 01 00:00:00 EST 2020

Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.

International journal of molecular medicine

Wang X,Lin L,Chai X,Wu Y,Li Y,Liu X

Wed Jan 01 00:00:00 EST 2020

Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.

Brain, behavior, and immunity

Liu X,Hao J,Yao E,Cao J,Zheng X,Yao D,Zhang C,Li J,Pan D,Luo X,Wang M,Wang W

Thu Oct 01 00:00:00 EDT 2020

Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.

Annals of translational medicine

Cheng H,Wu X,Ni G,Wang S,Peng W,Zhang H,Gao J,Li X

Sun Nov 01 00:00:00 EDT 2020

Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.

Cell biology international

Du MY,Duan JX,Zhang CY,Yang HH,Guan XX,Zhong WJ,Liu YZ,Li ZM,Cheng YR,Zhou Y,Guan CX

Wed Jan 01 00:00:00 EST 2020

LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.

Molecular biology reports

Yao L,Zhou B,You L,Hu H,Xie R

Wed Apr 01 00:00:00 EDT 2020

Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.

Human cell

Su L,Yao Y,Song W

Wed Apr 01 00:00:00 EDT 2020

hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β₁/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.

Stem cell research & therapy

Cui L,Bao H,Liu Z,Man X,Liu H,Hou Y,Luo Q,Wang S,Fu Q,Zhang H

Mon Sep 07 00:00:00 EDT 2020

Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response.

Biochemical pharmacology

Wu R,Zhang H,Zhao M,Li J,Hu Y,Fu J,Pi J,Wang H,Xu Y

Wed Apr 01 00:00:00 EDT 2020

Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.

Mediators of inflammation

Wang J,Li Y,Zhao P,Tian Y,Liu X,He H,Jia R,Oliver BG,Li J

Fri Jul 09 00:00:00 EDT 2021

MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.

Biomaterials

Wang T,Jian Z,Baskys A,Yang J,Li J,Guo H,Hei Y,Xian P,He Z,Li Z,Li N,Long Q

Thu Oct 01 00:00:00 EDT 2020

Sumoylation enhances the activity of the TGF-β/SMAD and HIF-1 signaling pathways in keloids.

Life sciences

Lin X,Wang Y,Jiang Y,Xu M,Pang Q,Sun J,Yu Y,Shen Z,Lei R,Xu J

Sat Aug 15 00:00:00 EDT 2020

Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.

Environmental pollution (Barking, Essex : 1987)

Li Z,Zhu S,Liu Q,Wei J,Jin Y,Wang X,Zhang L

Thu Oct 01 00:00:00 EDT 2020

Growth and Stem Cell Characteristics of Tendon-Derived Cells with Different Initial Seeding Densities: An In Vitro Study in Mouse Flexor Tendon Cells.

Stem cells and development

Wu YF,Chen C,Tang JB,Mao WF

Sat Aug 01 00:00:00 EDT 2020

MicroRNA-29a attenuates angiotensin-II induced-left ventricular remodeling by inhibiting collagen, TGF-β and SMAD2/3 expression.

Journal of geriatric cardiology : JGC

Zhang SJ,Yun CJ,Liu J,Yao SY,Li Y,Wang M,Wang C,Bai YY,Xue H

Sat Feb 01 00:00:00 EST 2020

Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway.

Molecular medicine reports

Xu X,Yu H,Sun L,Zheng C,Shan Y,Zhou Z,Wang C,Chen B

Wed Apr 01 00:00:00 EDT 2020

Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway.

Molecular medicine reports

Xu X,Yu H,Sun L,Zheng C,Shan Y,Zhou Z,Wang C,Chen B

Wed Apr 01 00:00:00 EDT 2020

Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.

Frontiers in physiology

Wu SJ,Lin ZH,Lin YZ,Rao ZH,Lin JF,Wu LP,Li L

Wed Apr 13 00:00:00 EDT 2022

Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.

Journal of pharmacological sciences

Tan Y,Li Y,Zhou F,Guo J,Wang T,Shi Y,Yang Y,Lu J,Pei G

Wed Jul 01 00:00:00 EDT 2020

Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-[Formula: see text]B Signaling Pathway.

The American journal of Chinese medicine

Ke SY,Liu DH,Wu L,Yu XG,Wang M,Shi GY,Wen RH,Zhou B,Hao BS,Liu Y,Zhu JM,Qian XX

Wed Oct 21 00:00:00 EDT 2020

Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TGF-β1-Smad signaling pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Feng F,Li N,Cheng P,Zhang H,Wang H,Wang Y,Wang W

Wed Jan 01 00:00:00 EST 2020

Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TGF-β1-Smad signaling pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Feng F,Li N,Cheng P,Zhang H,Wang H,Wang Y,Wang W

Wed Jan 01 00:00:00 EST 2020

Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TGF-β1-Smad signaling pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Feng F,Li N,Cheng P,Zhang H,Wang H,Wang Y,Wang W

Wed Jan 01 00:00:00 EST 2020

G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.

Journal of diabetes

Lai S,Fu X,Yang S,Zhang S,Lin Q,Zhang M,Chen H

Sun Mar 01 00:00:00 EST 2020

β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.

Aging

Wu Z,Yan M,Zhang M,Wu N,Ma G,Wang B,Fan Y,Du X,Ding C,Liu Y

Mon Dec 21 00:00:00 EST 2020

Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.

Cell death & disease

Wang J,Deng B,Liu Q,Huang Y,Chen W,Li J,Zhou Z,Zhang L,Liang B,He J,Chen Z,Yan C,Yang Z,Xian S,Wang L

Fri Jul 24 00:00:00 EDT 2020

Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zeng SY,Yang L,Yan QJ,Gao L,Lu HQ,Yan PK

Tue Jan 01 00:00:00 EST 2019

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zeng SY,Yang L,Yan QJ,Gao L,Lu HQ,Yan PK

Tue Jan 01 00:00:00 EST 2019

Catabolic changes of rat temporomandibular joint discs induced by unilateral anterior crossbite.

Journal of oral rehabilitation

Zhang HY,Xie MJ,Yang HX,Liu X,Ren HT,Zhang M,Lu L,Liu XD,Zhang J,Wang MQ

Mon Apr 01 00:00:00 EDT 2019

Catabolic changes of rat temporomandibular joint discs induced by unilateral anterior crossbite.

Journal of oral rehabilitation

Zhang HY,Xie MJ,Yang HX,Liu X,Ren HT,Zhang M,Lu L,Liu XD,Zhang J,Wang MQ

Mon Apr 01 00:00:00 EDT 2019

Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.

Biochemical and biophysical research communications

Zhang LM,Zhang Y,Fei C,Zhang J,Wang L,Yi ZW,Gao G

Tue Jan 08 00:00:00 EST 2019

Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.

Biochemical and biophysical research communications

Zhang LM,Zhang Y,Fei C,Zhang J,Wang L,Yi ZW,Gao G

Tue Jan 08 00:00:00 EST 2019

Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.

Gene

Gao J,Guo Y,Chen Y,Zhou J,Liu Y,Su P

Mon May 20 00:00:00 EDT 2019

Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression.

International journal of medical sciences

Kumagai M,Guo X,Wang KY,Izumi H,Tsukamoto M,Nakashima T,Tasaki T,Kurose N,Uramoto H,Sasaguri Y,Kohno K,Yamada S

Wed Jul 24 00:00:00 EDT 2019

Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis.

American journal of respiratory cell and molecular biology

Cui H,Xie N,Jiang D,Banerjee S,Ge J,Sanders YY,Liu G

Tue Oct 01 00:00:00 EDT 2019

The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.

Biochimica et biophysica acta. Molecular basis of disease

Liang JN,Zou X,Fang XH,Xu JD,Xiao Z,Zhu JN,Li H,Yang J,Zeng N,Yuan SJ,Pan R,Fu YH,Zhang M,Luo JF,Wang S,Shan ZX

Sun Sep 01 00:00:00 EDT 2019

Anti-inflammatory effects of hederagenin on diabetic cardiomyopathy via inhibiting NF-κB and Smads signaling pathways in a type-2 diabetic mice model.

RSC advances

Li Y,Dong J,Shang Y,Zhao Q,Li P,Wu B

Mon Aug 19 00:00:00 EDT 2019

The effect of topical ramipril and losartan cream in inhibiting scar formation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zheng B,Fang QQ,Wang XF,Shi BH,Zhao WY,Chen CY,Zhang MX,Zhang LY,Hu YY,Shi P,Ma L,Tan WQ

Tue Oct 01 00:00:00 EDT 2019

Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.

Molecular nutrition & food research

Zou LX,Chen C,Yan X,Lin QY,Fang J,Li PB,Han X,Wang QS,Guo SB,Li HH,Zhang YL

Sun Dec 01 00:00:00 EST 2019

LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.

Journal of molecular and cellular cardiology

Sun F,Zhuang Y,Zhu H,Wu H,Li D,Zhan L,Yang W,Yuan Y,Xie Y,Yang S,Luo S,Jiang W,Zhang J,Pan Z,Lu Y

Thu Aug 01 00:00:00 EDT 2019

The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.

Toxicology letters

Jiang R,Zhou Z,Liao Y,Yang F,Cheng Y,Huang J,Wang J,Chen H,Zhu T,Chao J

Sat Jun 01 00:00:00 EDT 2019

Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.

Journal of cellular and molecular medicine

Yang Z,Xiao Z,Guo H,Fang X,Liang J,Zhu J,Yang J,Li H,Pan R,Yuan S,Dong W,Zheng XL,Wu S,Shan Z

Wed May 01 00:00:00 EDT 2019

Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.

Journal of diabetes and its complications

Ding M,Fang QH,Cui YT,Shen QL,Liu Q,Wang PH,Yu DM,Li CJ

Mon Apr 01 00:00:00 EDT 2019

Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.

International journal of molecular sciences

Li R,Guo Y,Zhang Y,Zhang X,Zhu L,Yan T

Mon Mar 04 00:00:00 EST 2019

HBOA ameliorates CCl₄-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Sun X,Huang X,Zhu X,Liu L,Mo S,Wang H,Wei X,Lu S,Bai F,Wang D,Lin X,Lin J

Mon Jul 01 00:00:00 EDT 2019

Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation.

Theranostics

Chen W,Yuan H,Cao W,Wang T,Chen W,Yu H,Fu Y,Jiang B,Zhou H,Guo H,Zhao X

Mon Jul 27 00:00:00 EDT 2020

Interleukin-9 blockage reduces early hepatic granuloma formation and fibrosis during Schistosoma japonicum infection in mice.

Immunology

Zhan T,Ma H,Jiang S,Zhong Z,Wang X,Li C,Yu D,Liu L,Xu J,Xia C

Sun Dec 01 00:00:00 EST 2019

IMM-H007 improves heart function via reducing cardiac fibrosis.

European journal of pharmacology

Ge W,Zhang W,Gao R,Li B,Zhu H,Wang J

Thu Aug 15 00:00:00 EDT 2019

Concentrated Growth Factors Can Inhibit Photoaging Damage Induced by Ultraviolet A (UVA) on the Human Dermal Fibroblasts In Vitro.

Medical science monitor : international medical journal of experimental and clinical research

Chen J,Jiao D,Zhang M,Zhong S,Zhang T,Ren X,Ren G

Mon May 20 00:00:00 EDT 2019

Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite.

Aging cell

Del Campo L,Sánchez-López A,Salaices M,von Kleeck RA,Expósito E,González-Gómez C,Cussó L,Guzmán-Martínez G,Ruiz-Cabello J,Desco M,Assoian RK,Briones AM,Andrés V

Sat Jun 01 00:00:00 EDT 2019

SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu ZH,Zhang Y,Wang X,Fan XF,Zhang Y,Li X,Gong YS,Han LP

Tue Oct 01 00:00:00 EDT 2019

SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu ZH,Zhang Y,Wang X,Fan XF,Zhang Y,Li X,Gong YS,Han LP

Tue Oct 01 00:00:00 EDT 2019

Presence and function of stress granules in atrial fibrillation.

PloS one

Dong G,Liang F,Sun B,Wang C,Liu Y,Guan X,Yang B,Xiu C,Yang N,Liu F,Lu T,Han W

Tue Dec 31 00:00:00 EST 2019

Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.

Biomolecules

Chen TT,Peng S,Wang Y,Hu Y,Shen Y,Xu Y,Yin J,Liu C,Cao J

Fri Oct 25 00:00:00 EDT 2019

Blockade of lncRNA-ASLNCS5088-enriched exosome generation in M2 macrophages by GW4869 dampens the effect of M2 macrophages on orchestrating fibroblast activation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen J,Zhou R,Liang Y,Fu X,Wang D,Wang C

Fri Nov 01 00:00:00 EDT 2019

Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.

International journal of molecular medicine

Yang R,Jia Q,Ma SF,Wang Y,Mehmood S,Chen Y

Thu Aug 01 00:00:00 EDT 2019

Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.

Clinical science (London, England : 1979)

Xue M,Li T,Wang Y,Chang Y,Cheng Y,Lu Y,Liu X,Xu L,Li X,Yu X,Sun B,Chen L

Thu Aug 15 00:00:00 EDT 2019

Calhex₂₃₁ Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.

Biological & pharmaceutical bulletin

Yuan H,Xu J,Xu X,Gao T,Wang Y,Fan Y,Hu J,Shao Y,Zhao B,Li H,Sun J,Xu C

Thu Aug 01 00:00:00 EDT 2019

Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.

Journal of cellular and molecular medicine

Lin ZH,Li YC,Wu SJ,Zheng C,Lin YZ,Lian H,Lin WQ,Lin JF

Mon Jul 01 00:00:00 EDT 2019

Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.

Frontiers in pharmacology

Liu X,Shan X,Chen H,Li Z,Zhao P,Zhang C,Guo W,Xu M,Lu R

Thu Oct 01 00:00:00 EDT 2020

Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.

American journal of respiratory cell and molecular biology

Ge J,Cui H,Xie N,Banerjee S,Guo S,Dubey S,Barnes S,Liu G

Thu Mar 01 00:00:00 EST 2018

Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.

American journal of respiratory cell and molecular biology

Ge J,Cui H,Xie N,Banerjee S,Guo S,Dubey S,Barnes S,Liu G

Thu Mar 01 00:00:00 EST 2018

Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Bai Y,Zhang Y,Han B,Yang L,Chen X,Huang R,Wu F,Chao J,Liu P,Hu G,Zhang JH,Yao H

Wed Jan 03 00:00:00 EST 2018

Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Bai Y,Zhang Y,Han B,Yang L,Chen X,Huang R,Wu F,Chao J,Liu P,Hu G,Zhang JH,Yao H

Wed Jan 03 00:00:00 EST 2018

Overexpression of collagen type III in injured myocardium prevents cardiac systolic dysfunction by changing the balance of collagen distribution.

The Journal of thoracic and cardiovascular surgery

Uchinaka A,Yoshida M,Tanaka K,Hamada Y,Mori S,Maeno Y,Miyagawa S,Sawa Y,Nagata K,Yamamoto H,Kawaguchi N

Sun Jul 01 00:00:00 EDT 2018

Overexpression of collagen type III in injured myocardium prevents cardiac systolic dysfunction by changing the balance of collagen distribution.

The Journal of thoracic and cardiovascular surgery

Uchinaka A,Yoshida M,Tanaka K,Hamada Y,Mori S,Maeno Y,Miyagawa S,Sawa Y,Nagata K,Yamamoto H,Kawaguchi N

Sun Jul 01 00:00:00 EDT 2018

Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.

Journal of immunology (Baltimore, Md. : 1950)

Tang S,Deng S,Guo J,Chen X,Zhang W,Cui Y,Luo Y,Yan Z,He QY,Shen S,Wang T

Mon Jan 15 00:00:00 EST 2018

Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.

Journal of immunology (Baltimore, Md. : 1950)

Tang S,Deng S,Guo J,Chen X,Zhang W,Cui Y,Luo Y,Yan Z,He QY,Shen S,Wang T

Mon Jan 15 00:00:00 EST 2018

Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.

Chinese medicine

Wang Q,Zang W,Han L,Yang L,Ye S,Ouyang J,Zhang C,Bi Y,Zhang C,Bian H

Fri Apr 08 00:00:00 EDT 2022

Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.

Chinese medicine

Wang Q,Zang W,Han L,Yang L,Ye S,Ouyang J,Zhang C,Bi Y,Zhang C,Bian H

Fri Apr 08 00:00:00 EDT 2022

Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.

Cell biology international

Zhang F,Wan X,Cao YZ,Sun D,Cao CC

Sat Dec 01 00:00:00 EST 2018

Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury.

Cell biology international

Zhang F,Wan X,Cao YZ,Sun D,Cao CC

Sat Dec 01 00:00:00 EST 2018

Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.

Toxicology and applied pharmacology

Zhao X,Qu G,Song C,Li R,Liu W,Lv C,Song X,Zhang J,Li M

Mon Oct 01 00:00:00 EDT 2018

Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.

Toxicology and applied pharmacology

Zhao X,Qu G,Song C,Li R,Liu W,Lv C,Song X,Zhang J,Li M

Mon Oct 01 00:00:00 EDT 2018

Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.

Archives of biochemistry and biophysics

Xiao Y,Ye J,Zhou Y,Huang J,Liu X,Huang B,Zhu L,Wu B,Zhang G,Cai Y

Thu Feb 15 00:00:00 EST 2018

Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.

Archives of biochemistry and biophysics

Xiao Y,Ye J,Zhou Y,Huang J,Liu X,Huang B,Zhu L,Wu B,Zhang G,Cai Y

Thu Feb 15 00:00:00 EST 2018

Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.

Radiation research

Qin W,Liu B,Yi M,Li L,Tang Y,Wu B,Yuan X

Mon Oct 01 00:00:00 EDT 2018

Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.

Radiation research

Qin W,Liu B,Yi M,Li L,Tang Y,Wu B,Yuan X

Mon Oct 01 00:00:00 EDT 2018

Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction.

American journal of physiology. Regulatory, integrative and comparative physiology

Chuang TD,Sakurai R,Gong M,Khorram O,Rehan VK

Thu Nov 01 00:00:00 EDT 2018

Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction.

American journal of physiology. Regulatory, integrative and comparative physiology

Chuang TD,Sakurai R,Gong M,Khorram O,Rehan VK

Thu Nov 01 00:00:00 EDT 2018

Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction.

American journal of physiology. Regulatory, integrative and comparative physiology

Chuang TD,Sakurai R,Gong M,Khorram O,Rehan VK

Thu Nov 01 00:00:00 EDT 2018

Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction.

American journal of physiology. Regulatory, integrative and comparative physiology

Chuang TD,Sakurai R,Gong M,Khorram O,Rehan VK

Thu Nov 01 00:00:00 EDT 2018

Flavonoid Extract from Propolis Inhibits Cardiac Fibrosis Triggered by Myocardial Infarction through Upregulation of SIRT1.

Evidence-based complementary and alternative medicine : eCAM

Wang Q,Sui X,Sui DJ,Yang P

Thu Oct 01 00:00:00 EDT 2020

Flavonoid Extract from Propolis Inhibits Cardiac Fibrosis Triggered by Myocardial Infarction through Upregulation of SIRT1.

Evidence-based complementary and alternative medicine : eCAM

Wang Q,Sui X,Sui DJ,Yang P

Thu Oct 01 00:00:00 EDT 2020

TGF-β1/Smad3 signaling promotes collagen synthesis in pulmonary artery smooth muscle by down-regulating miR-29b.

International journal of clinical and experimental pathology

Wang T,Li Y,Chen J,Xie L,Xiao T

Wed Mar 25 00:00:00 EDT 2020

Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang.

Clinical and experimental pharmacology & physiology

No authors listed

Wed Aug 01 00:00:00 EDT 2018

Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

He FF,You RY,Ye C,Lei CT,Tang H,Su H,Zhang C

Thu Jul 05 00:00:00 EDT 2018

Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

He FF,You RY,Ye C,Lei CT,Tang H,Su H,Zhang C

Thu Jul 05 00:00:00 EDT 2018

Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.

PloS one

Wang KY,Yamada S,Izumi H,Tsukamoto M,Nakashima T,Tasaki T,Guo X,Uramoto H,Sasaguri Y,Kohno K

Tue Jul 24 00:00:00 EDT 2018

Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.

PloS one

Wang KY,Yamada S,Izumi H,Tsukamoto M,Nakashima T,Tasaki T,Guo X,Uramoto H,Sasaguri Y,Kohno K

Tue Jul 24 00:00:00 EDT 2018

Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.

PloS one

Wang KY,Yamada S,Izumi H,Tsukamoto M,Nakashima T,Tasaki T,Guo X,Uramoto H,Sasaguri Y,Kohno K

Tue Jul 24 00:00:00 EDT 2018

Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.

RSC advances

Pei Z,Hu J,Bai Q,Liu B,Cheng D,Liu H,Na R,Yu Q

Tue Apr 17 00:00:00 EDT 2018

Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.

World journal of gastroenterology

Sang L,Wang XM,Xu DY,Sang LX,Han Y,Jiang LY

Thu Dec 21 00:00:00 EST 2017

Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.

World journal of gastroenterology

Sang L,Wang XM,Xu DY,Sang LX,Han Y,Jiang LY

Thu Dec 21 00:00:00 EST 2017

Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.

Surgery

Yoshida T,Fukumoto T,Urade T,Kido M,Toyama H,Asari S,Ajiki T,Ikeo N,Mukai T,Ku Y

Thu Jun 01 00:00:00 EDT 2017

Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.

Surgery

Yoshida T,Fukumoto T,Urade T,Kido M,Toyama H,Asari S,Ajiki T,Ikeo N,Mukai T,Ku Y

Thu Jun 01 00:00:00 EDT 2017

Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.

Biochemical and biophysical research communications

Yuan Y,Zhang Y,Han X,Li Y,Zhao X,Sheng L,Li Y

Sat Dec 02 00:00:00 EST 2017

Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.

Biochemical and biophysical research communications

Yuan Y,Zhang Y,Han X,Li Y,Zhao X,Sheng L,Li Y

Sat Dec 02 00:00:00 EST 2017

MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.

Scientific reports

Lei CT,Tang H,Ye C,You CQ,Zhang J,Zhang CY,Xiong W,Su H,Zhang C

Mon Sep 04 00:00:00 EDT 2017

MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.

Scientific reports

Lei CT,Tang H,Ye C,You CQ,Zhang J,Zhang CY,Xiong W,Su H,Zhang C

Mon Sep 04 00:00:00 EDT 2017

Crucial Role of miR-433 in Regulating Cardiac Fibrosis.

Theranostics

Tao L,Bei Y,Chen P,Lei Z,Fu S,Zhang H,Xu J,Che L,Chen X,Sluijter JP,Das S,Cretoiu D,Xu B,Zhong J,Xiao J,Li X

Mon Oct 16 00:00:00 EDT 2017

Bioinformatics

Protein Aliases: alpha1 (III) collagen; COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; Collagen3; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1

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Gene Aliases: AW550625; Col3a-1; COL3A1; EDS4A; mKIAA4231; MMS10-W; Ms10w

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UniProt ID: (Human) P02461, (Mouse) P08121, (Rat) P13941

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Entrez Gene ID: (Human) 1281, (Mouse) 12825, (Rat) 84032

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Function(s)

integrin binding extracellular matrix structural constituent protein binding SMAD binding metal ion binding platelet-derived growth factor binding molecular_function extracellular matrix structural protein

Process(es)

skeletal system development cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway heart development aging response to radiation response to mechanical stimulus peptide cross-linking cerebral cortex development platelet activation extracellular matrix organization collagen fibril organization collagen catabolic process response to cytokine positive regulation of Rho protein signal transduction wound healing extracellular fibril organization skin development digestive tract development regulation of immune response negative regulation of immune response aorta smooth muscle tissue morphogenesis cellular response to amino acid stimulus negative regulation of neuron migration blood vessel development

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Collagen Type III (N-terminal) Polyclonal Antibody

Collagen Type III (N-terminal) Antibody (22734-1-AP) in IHC (P)

Product Details

22734-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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