Product References
The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice.
Cellular and molecular life sciences : CMLS
Li Q,Cui C,Liao R,Yin X,Wang D,Cheng Y,Huang B,Wang L,Yan M,Zhou J,Zhao J,Tang W,Wang Y,Wang X,Lv J,Li J,Li H,Shu Y
51-2800 was used in Western Blotting to provide ideal mouse models for understanding the pathogenic mechanism of DFNB1A-related hereditary deafness and opens up a new avenue for investigating the treatment of this disease.
Sat May 13 00:00:00 EDT 2023
The prognostic value and biological significance of gap junction beta protein 2 (GJB2 or Cx26) in cervical cancer.
Frontiers in oncology
Meng S,Liu Y,Wang X,Wu X,Xie W,Kang X,Liu X,Guo L,Wang C
51-2800 was used in Immunohistochemistry to explore the prognostic significance of GJB2 and its function in cervical cancer (CC).
Tue Aug 09 00:00:00 EDT 2022
Expression of connexins and pannexins in diseased human liver.
EXCLI journal
Leroy K,Vilas-Boas V,Gijbels E,Vanderborght B,Devisscher L,Cogliati B,Van Den Bossche B,Colle I,Vinken M
51-2800 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to characterize the expression and subcellular localization of connexins and pannexins in liver of patients suffering from various chronic and neoplastic liver diseases.
Thu Nov 17 00:00:00 EST 2022
Expression of connexins and pannexins in diseased human liver.
EXCLI journal
Leroy K,Vilas-Boas V,Gijbels E,Vanderborght B,Devisscher L,Cogliati B,Van Den Bossche B,Colle I,Vinken M
51-2800 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to characterize the expression and subcellular localization of connexins and pannexins in liver of patients suffering from various chronic and neoplastic liver diseases.
Thu Nov 17 00:00:00 EST 2022
The protective effects of systemic dexamethasone on sensory epithelial damage and hearing loss in targeted Cx26-null mice.
Cell death & disease
Xu K,Chen S,Xie L,Qiu Y,Liu XZ,Bai X,Jin Y,Wang XH,Sun Y
51-2800 was used in Immunohistochemistry-immunofluorescence to suggest that the protective effect of dexamethasone on cochlear sensory epithelial damage and partially rescue auditory function may be related to the regulation of inner ear immune response in Cx26 deficiency mouse models.
Fri Jun 10 00:00:00 EDT 2022
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing.
Cancers
Nardin C,Peres C,Putti S,Orsini T,Colussi C,Mazzarda F,Raspa M,Scavizzi F,Salvatore AM,Chiani F,Tettey-Matey A,Kuang Y,Yang G,Retamal MA,Mammano F
51-2800 was used in Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry to demonstrate that HCs can be exploited to dramatically increase cytotoxic bystander effects and reveal a previously unappreciated role for HCs in tumor eradication promoted by PDT.
Sun Oct 10 00:00:00 EDT 2021
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing.
Cancers
Nardin C,Peres C,Putti S,Orsini T,Colussi C,Mazzarda F,Raspa M,Scavizzi F,Salvatore AM,Chiani F,Tettey-Matey A,Kuang Y,Yang G,Retamal MA,Mammano F
51-2800 was used in Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry to demonstrate that HCs can be exploited to dramatically increase cytotoxic bystander effects and reveal a previously unappreciated role for HCs in tumor eradication promoted by PDT.
Sun Oct 10 00:00:00 EDT 2021
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing.
Cancers
Nardin C,Peres C,Putti S,Orsini T,Colussi C,Mazzarda F,Raspa M,Scavizzi F,Salvatore AM,Chiani F,Tettey-Matey A,Kuang Y,Yang G,Retamal MA,Mammano F
51-2800 was used in Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry to demonstrate that HCs can be exploited to dramatically increase cytotoxic bystander effects and reveal a previously unappreciated role for HCs in tumor eradication promoted by PDT.
Sun Oct 10 00:00:00 EDT 2021
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing.
Cancers
Nardin C,Peres C,Putti S,Orsini T,Colussi C,Mazzarda F,Raspa M,Scavizzi F,Salvatore AM,Chiani F,Tettey-Matey A,Kuang Y,Yang G,Retamal MA,Mammano F
51-2800 was used in Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry to demonstrate that HCs can be exploited to dramatically increase cytotoxic bystander effects and reveal a previously unappreciated role for HCs in tumor eradication promoted by PDT.
Sun Oct 10 00:00:00 EDT 2021
Functional Evaluation of a Rare Variant c.516G>C (p.Trp172Cys) in the GJB2 (Connexin 26) Gene Associated with Nonsyndromic Hearing Loss.
Biomolecules
Maslova EA,Orishchenko KE,Posukh OL
51-2800 was used in Immunocytochemistry, Western Blot to contribute to a better understanding of the role of mutations in the second extracellular loop of Cx26 protein in pathogenesis of deafness.
Tue Jan 05 00:00:00 EST 2021
Functional Evaluation of a Rare Variant c.516G>C (p.Trp172Cys) in the GJB2 (Connexin 26) Gene Associated with Nonsyndromic Hearing Loss.
Biomolecules
Maslova EA,Orishchenko KE,Posukh OL
51-2800 was used in Immunocytochemistry, Western Blot to contribute to a better understanding of the role of mutations in the second extracellular loop of Cx26 protein in pathogenesis of deafness.
Tue Jan 05 00:00:00 EST 2021
Functional Evaluation of a Rare Variant c.516G>C (p.Trp172Cys) in the GJB2 (Connexin 26) Gene Associated with Nonsyndromic Hearing Loss.
Biomolecules
Maslova EA,Orishchenko KE,Posukh OL
51-2800 was used in Immunocytochemistry, Western Blot to contribute to a better understanding of the role of mutations in the second extracellular loop of Cx26 protein in pathogenesis of deafness.
Tue Jan 05 00:00:00 EST 2021
Functional Evaluation of a Rare Variant c.516G>C (p.Trp172Cys) in the GJB2 (Connexin 26) Gene Associated with Nonsyndromic Hearing Loss.
Biomolecules
Maslova EA,Orishchenko KE,Posukh OL
51-2800 was used in Immunocytochemistry, Western Blot to contribute to a better understanding of the role of mutations in the second extracellular loop of Cx26 protein in pathogenesis of deafness.
Tue Jan 05 00:00:00 EST 2021
Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway.
International journal of molecular sciences
Kim YJ,Lee JS,Kim H,Jang JH,Choung YH
51-2800 was used in Immunohistochemistry to identify specific small molecules that pass through gap junctions in the process of CDDP-induced auditory cell death and suggest new mechanisms to prevent hearing loss.
Sun Jun 13 00:00:00 EDT 2021
Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway.
International journal of molecular sciences
Kim YJ,Lee JS,Kim H,Jang JH,Choung YH
51-2800 was used in Immunohistochemistry to identify specific small molecules that pass through gap junctions in the process of CDDP-induced auditory cell death and suggest new mechanisms to prevent hearing loss.
Sun Jun 13 00:00:00 EDT 2021
Expression and Functionality of Connexin-Based Channels in Human Liver Cancer Cell Lines.
International journal of molecular sciences
Leroy K,Silva Costa CJ,Pieters A,Dos Santos Rodrigues B,Van Campenhout R,Cooreman A,Tabernilla A,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Western Blot
Wed Nov 10 00:00:00 EST 2021
Expression and Functionality of Connexin-Based Channels in Human Liver Cancer Cell Lines.
International journal of molecular sciences
Leroy K,Silva Costa CJ,Pieters A,Dos Santos Rodrigues B,Van Campenhout R,Cooreman A,Tabernilla A,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Western Blot
Wed Nov 10 00:00:00 EST 2021
Connexin-Based Channel Activity Is Not Specifically Altered by Hepatocarcinogenic Chemicals.
International journal of molecular sciences
Leroy K,Pieters A,Cooreman A,Van Campenhout R,Cogliati B,Vinken M
51-2800 was used in Western Blot, Immunocytochemistry to investigate the effects of various genotoxic carcinogenic compounds, non-genotoxic carcinogenic compounds and non-carcinogenic compounds on the expression and functionality of connexin-based channels, both gap junctions and connexin hemichannels.
Fri Oct 29 00:00:00 EDT 2021
Connexin-Based Channel Activity Is Not Specifically Altered by Hepatocarcinogenic Chemicals.
International journal of molecular sciences
Leroy K,Pieters A,Cooreman A,Van Campenhout R,Cogliati B,Vinken M
51-2800 was used in Western Blot, Immunocytochemistry to investigate the effects of various genotoxic carcinogenic compounds, non-genotoxic carcinogenic compounds and non-carcinogenic compounds on the expression and functionality of connexin-based channels, both gap junctions and connexin hemichannels.
Fri Oct 29 00:00:00 EDT 2021
PUPIL enables mapping and stamping of transient electrical connectivity in developing nervous systems.
Cell reports
Xie S,Li H,Yao F,Huang J,Yang X,Chen X,Liu Q,Zhuang M,He S
51-2800 was used in Immunohistochemistry to develop pupylation-based interaction labeling (PUPIL), a genetically encoded system for noninvasively mapping and stamping transient electrical synapses in the mouse brain.
Tue Oct 19 00:00:00 EDT 2021
Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release.
Frontiers in cellular neuroscience
Chen J,Chen P,He B,Gong T,Li Y,Zhang J,Lv J,Mammano F,Hou S,Yang J
51-2800 was used in Immunohistochemistry to conclude that Cx30 may play an important rather than redundant role in hearing development.
Fri Feb 04 00:00:00 EST 2022
Single cell transcriptomics of human epidermis identifies basal stem cell transition states.
Nature communications
Wang S,Drummond ML,Guerrero-Juarez CF,Tarapore E,MacLean AL,Stabell AR,Wu SC,Gutierrez G,That BT,Benavente CA,Nie Q,Atwood SX
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Tue Aug 25 00:00:00 EDT 2020
Single cell transcriptomics of human epidermis identifies basal stem cell transition states.
Nature communications
Wang S,Drummond ML,Guerrero-Juarez CF,Tarapore E,MacLean AL,Stabell AR,Wu SC,Gutierrez G,That BT,Benavente CA,Nie Q,Atwood SX
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Tue Aug 25 00:00:00 EDT 2020
Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by atomic force microscopy imaging.
The Journal of biological chemistry
Naulin PA,Lozano B,Fuentes C,Liu Y,Schmidt C,Contreras JE,Barrera NP
51-2800 was used in Western Blotting to report, for the first time, the molecular architecture of Cx heteromeric hemichannels, which could have profound implications on their biophysical properties versus homomeric species.
Fri Dec 04 00:00:00 EST 2020
Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by atomic force microscopy imaging.
The Journal of biological chemistry
Naulin PA,Lozano B,Fuentes C,Liu Y,Schmidt C,Contreras JE,Barrera NP
51-2800 was used in Western Blotting to report, for the first time, the molecular architecture of Cx heteromeric hemichannels, which could have profound implications on their biophysical properties versus homomeric species.
Fri Dec 04 00:00:00 EST 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Sep 07 00:00:00 EDT 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Sep 07 00:00:00 EDT 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Sep 07 00:00:00 EDT 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Sep 07 00:00:00 EDT 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Sep 07 00:00:00 EDT 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Sep 07 00:00:00 EDT 2020
Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes.
Biomolecules
Au A,Shao Q,White KK,Lucaciu SA,Esseltine JL,Barr K,Laird DW
51-2800 was used in Immunocytochemistry-immunoflourescence to study the role of the principal connexin Cx43 in rodent keratinocyte differentiation.
Wed Oct 14 00:00:00 EDT 2020
Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes.
Biomolecules
Au A,Shao Q,White KK,Lucaciu SA,Esseltine JL,Barr K,Laird DW
51-2800 was used in Immunocytochemistry-immunoflourescence to study the role of the principal connexin Cx43 in rodent keratinocyte differentiation.
Wed Oct 14 00:00:00 EDT 2020
Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model.
Disease models & mechanisms
Chen S,Xie L,Xu K,Cao HY,Wu X,Xu XX,Sun Y,Kong WJ
51-2800 was used in Western Blotting to study the pathological changes and the mechanism behind the cochlear abnormalities in connexin26-null mice.
Mon Feb 26 00:00:00 EST 2018
Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model.
Disease models & mechanisms
Chen S,Xie L,Xu K,Cao HY,Wu X,Xu XX,Sun Y,Kong WJ
51-2800 was used in Western Blotting to study the pathological changes and the mechanism behind the cochlear abnormalities in connexin26-null mice.
Mon Feb 26 00:00:00 EST 2018
The spatial distribution pattern of Connexin26 expression in supporting cells and its role in outer hair cell survival.
Cell death & disease
Chen S,Xu K,Xie L,Cao HY,Wu X,Du AN,He ZH,Lin X,Sun Y,Kong WJ
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Wed Dec 05 00:00:00 EST 2018
The spatial distribution pattern of Connexin26 expression in supporting cells and its role in outer hair cell survival.
Cell death & disease
Chen S,Xu K,Xie L,Cao HY,Wu X,Du AN,He ZH,Lin X,Sun Y,Kong WJ
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Wed Dec 05 00:00:00 EST 2018
Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function.
Frontiers in molecular neuroscience
Zorzi V,Paciello F,Ziraldo G,Peres C,Mazzarda F,Nardin C,Pasquini M,Chiani F,Raspa M,Scavizzi F,Carrer A,Crispino G,Ciubotaru CD,Monyer H,Fetoni AR,M Salvatore A,Mammano F
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Western Blot
Thu Oct 01 00:00:00 EDT 2020
Immunofluorescence reveals unusual patterns of labelling for connexin43 localized to calbindin-D28K-positive interstitial cells in the pineal gland.
The European journal of neuroscience
Tsao DD,Wang SG,Lynn BD,Nagy JI
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunofluorescence
Thu Jun 01 00:00:00 EDT 2017
In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors.
Scientific reports
Crispino G,Galindo Ramirez F,Campioni M,Zorzi V,Praetorius M,Di Pasquale G,Chiorini JA,Mammano F
Fri Aug 04 00:00:00 EDT 2017
Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice.
Cell death & disease
Press E,Alaga KC,Barr K,Shao Q,Bosen F,Willecke K,Laird DW
51-2800 was used in Immunofluorescence in immunohistochemistry on frozen tissues to suggest that the Cx26S17F mutant disturbs keratinocyte differentiation and epidermal remodeling following wound closure.
Thu Jun 01 00:00:00 EDT 2017
Connexin gap junction channels and chronic rhinosinusitis.
International forum of allergy & rhinology
Kim R,Chang G,Hu R,Phillips A,Douglas R
51-2800 was used in immunohistochemistry - frozen section to learn the connection between chronic rhinosinusitis and connexin gap junction channels
Wed Jun 01 00:00:00 EDT 2016
Connexin gap junction channels and chronic rhinosinusitis.
International forum of allergy & rhinology
Kim R,Chang G,Hu R,Phillips A,Douglas R
51-2800 was used in immunohistochemistry - frozen section to learn the connection between chronic rhinosinusitis and connexin gap junction channels
Wed Jun 01 00:00:00 EDT 2016
Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.
Journal of cell science
Polusani SR,Kalmykov EA,Chandrasekhar A,Zucker SN,Nicholson BJ
51-2800 was used in Immunocytochemistry-immunoflourescence to show that expression of Cx26 in HeLa cells specifically enhances cell motility in scrape wounding and sparse culture models.
Thu Dec 01 00:00:00 EST 2016
Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis.
PloS one
Stewart MK,Plante I,Penuela S,Laird DW
51-2800 was used in immunohistochemistry - frozen section to investigate breast tumorigenesis due to loss of Panx1 which impairs mammary gland development at lactation
Wed Apr 05 00:00:00 EDT 2017
Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing.
Neurobiology of disease
Chang Q,Tang W,Kim Y,Lin X
51-2800 was used in immunocytochemistry to show that Gjb2 is required for normal Corti development in mice
Thu Jan 01 00:00:00 EST 2015
Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions.
Journal of cell science
Kelly JJ,Shao Q,Jagger DJ,Laird DW
51-2800 was used in immunocytochemistry to study the synthesis and localization of connexin 30.
Sun Nov 01 00:00:00 EDT 2015
Mice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organs.
Hearing research
Lee MY,Takada T,Takada Y,Kappy MD,Beyer LA,Swiderski DL,Godin AL,Brewer S,King WM,Raphael Y
51-2800 was used in immunohistochemistry to study vestibular dysfunction and organ pathology in connexin-26 knock out mice.
Thu Oct 01 00:00:00 EDT 2015
Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.
Developmental biology
Mroue R,Inman J,Mott J,Budunova I,Bissell MJ
51-2800 was used in immunohistochemistry (paraffin) and western blot to test if K5-Cx26 mothers fail to eject the milk.
Sun Mar 01 00:00:00 EST 2015
Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.
Developmental biology
Mroue R,Inman J,Mott J,Budunova I,Bissell MJ
51-2800 was used in immunohistochemistry (paraffin) and western blot to test if K5-Cx26 mothers fail to eject the milk.
Sun Mar 01 00:00:00 EST 2015
Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.
Developmental biology
Mroue R,Inman J,Mott J,Budunova I,Bissell MJ
51-2800 was used in immunohistochemistry (paraffin) and western blot to test if K5-Cx26 mothers fail to eject the milk.
Sun Mar 01 00:00:00 EST 2015
Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer.
Oncotarget
Stewart MK,Bechberger JF,Welch I,Naus CC,Laird DW
51-2800 was used in immunohistochemistry to discuss Cx26 knockout in DMBA-induced mouse models and breast cancer
Tue Nov 10 00:00:00 EST 2015
Ototoxicity-induced loss of hearing and inner hair cells is attenuated by HSP70 gene transfer.
Molecular therapy. Methods & clinical development
Takada Y,Takada T,Lee MY,Swiderski DL,Kabara LL,Dolan DF,Raphael Y
51-2800 was used in immunohistochemistry to learn about attenuation of hearing loss due to innher hair cell loss by HSP70 gene transfer induced by ototoxicity
Mon Jun 01 00:00:00 EDT 2015
Re-evaluation of connexins associated with motoneurons in rodent spinal cord, sexually dimorphic motor nuclei and trigeminal motor nucleus.
The European journal of neuroscience
Bautista W,Rash JE,Vanderpool KG,Yasumura T,Nagy JI
51-2800 was used in immunocytochemistry to characterize connexins associated with motoneurons in rodent spinal cord, sexually dimorphic motor nuclei and trigeminal motor nucleus
Sat Mar 01 00:00:00 EST 2014
Re-evaluation of connexins associated with motoneurons in rodent spinal cord, sexually dimorphic motor nuclei and trigeminal motor nucleus.
The European journal of neuroscience
Bautista W,Rash JE,Vanderpool KG,Yasumura T,Nagy JI
51-2800 was used in immunocytochemistry to characterize connexins associated with motoneurons in rodent spinal cord, sexually dimorphic motor nuclei and trigeminal motor nucleus
Sat Mar 01 00:00:00 EST 2014
Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy.
Hearing research
Takada Y,Beyer LA,Swiderski DL,O'Neal AL,Prieskorn DM,Shivatzki S,Avraham KB,Raphael Y
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunocytochemistry
Sat Mar 01 00:00:00 EST 2014
Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy.
Hearing research
Takada Y,Beyer LA,Swiderski DL,O'Neal AL,Prieskorn DM,Shivatzki S,Avraham KB,Raphael Y
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunocytochemistry
Sat Mar 01 00:00:00 EST 2014
Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function.
PloS one
Stewart MK,Plante I,Bechberger JF,Naus CC,Laird DW
51-2800 was used in immunocytochemistry to determine if patients with loss-of-function Cx26 mutations have a greater susceptibility to impaired breast development
Tue Oct 20 00:00:00 EDT 2015
Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function.
PloS one
Stewart MK,Plante I,Bechberger JF,Naus CC,Laird DW
51-2800 was used in immunocytochemistry to determine if patients with loss-of-function Cx26 mutations have a greater susceptibility to impaired breast development
Tue Oct 20 00:00:00 EDT 2015
Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function.
PloS one
Stewart MK,Plante I,Bechberger JF,Naus CC,Laird DW
51-2800 was used in immunocytochemistry to determine if patients with loss-of-function Cx26 mutations have a greater susceptibility to impaired breast development
Tue Oct 20 00:00:00 EDT 2015
Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo.
The Journal of biological chemistry
Ableser MJ,Penuela S,Lee J,Shao Q,Laird DW
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunocytochemistry
Fri Jan 17 00:00:00 EST 2014
Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo.
The Journal of biological chemistry
Ableser MJ,Penuela S,Lee J,Shao Q,Laird DW
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunocytochemistry
Fri Jan 17 00:00:00 EST 2014
The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus.
Journal of proteome research
Fowler SL,Akins M,Zhou H,Figeys D,Bennett SA
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunoprecipitation
Fri Jun 07 00:00:00 EDT 2013
The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus.
Journal of proteome research
Fowler SL,Akins M,Zhou H,Figeys D,Bennett SA
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunoprecipitation
Fri Jun 07 00:00:00 EDT 2013
Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia.
Neuropharmacology
Kozoriz MG,Lai S,Vega JL,Sáez JC,Sin WC,Bechberger JF,Naus CC
51-2800 was used in western blot to assess the effect of the +/G60S mutation in connexin 43 following stroke.
Sun Dec 01 00:00:00 EST 2013
The D50N mutation and syndromic deafness: altered Cx26 hemichannel properties caused by effects on the pore and intersubunit interactions.
The Journal of general physiology
Sanchez HA,Villone K,Srinivas M,Verselis VK
Mon Jul 01 00:00:00 EDT 2013
Focal adhesion kinase modulates radial glia-dependent neuronal migration through connexin-26.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Valiente M,Ciceri G,Rico B,Marín O
51-2800 was used in immunohistochemistry - frozen section to examine the function of focal adhesion kinase in cortical interneurons and pyramidal cells.
Wed Aug 10 00:00:00 EDT 2011
Dominant Cx26 mutants associated with hearing loss have dominant-negative effects on wild type Cx26.
Molecular and cellular neurosciences
Zhang J,Scherer SS,Yum SW
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunofluorescence
Wed Jun 01 00:00:00 EDT 2011
Dominant Cx26 mutants associated with hearing loss have dominant-negative effects on wild type Cx26.
Molecular and cellular neurosciences
Zhang J,Scherer SS,Yum SW
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunofluorescence
Wed Jun 01 00:00:00 EDT 2011
Dominant Cx26 mutants associated with hearing loss have dominant-negative effects on wild type Cx26.
Molecular and cellular neurosciences
Zhang J,Scherer SS,Yum SW
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunofluorescence
Wed Jun 01 00:00:00 EDT 2011
Reduced gap junctional communication among astrocytes in experimental diabetes: contributions of altered connexin protein levels and oxidative-nitrosative modifications.
Journal of neuroscience research
Ball KK,Harik L,Gandhi GK,Cruz NF,Dienel GA
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Western Blot
Thu Dec 01 00:00:00 EST 2011
Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic mice.
The European journal of neuroscience
Nagy JI,Lynn BD,Tress O,Willecke K,Rash JE
51-2800 was used in western blot to study connexin 26 in astrocytes.
Fri Jul 01 00:00:00 EDT 2011
Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic mice.
The European journal of neuroscience
Nagy JI,Lynn BD,Tress O,Willecke K,Rash JE
51-2800 was used in western blot to study connexin 26 in astrocytes.
Fri Jul 01 00:00:00 EDT 2011
Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic mice.
The European journal of neuroscience
Nagy JI,Lynn BD,Tress O,Willecke K,Rash JE
51-2800 was used in western blot to study connexin 26 in astrocytes.
Fri Jul 01 00:00:00 EDT 2011
Ablation of connexin30 in transgenic mice alters expression patterns of connexin26 and connexin32 in glial cells and leptomeninges.
The European journal of neuroscience
Lynn BD,Tress O,May D,Willecke K,Nagy JI
51-2800 was used in immunohistochemistry (frozen) to study localization of connexins in the brain.
Thu Dec 01 00:00:00 EST 2011
BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice.
PloS one
Crispino G,Di Pasquale G,Scimemi P,Rodriguez L,Galindo Ramirez F,De Siati RD,Santarelli RM,Arslan E,Bortolozzi M,Chiorini JA,Mammano F
51-2800 was used in immunohistochemistry to study the expression and function of connexin26 and connexin30 in the ears of transgenic mice.
Fri Dec 30 00:00:00 EST 2011
Dominant connexin26 mutants associated with human hearing loss have trans-dominant effects on connexin30.
Neurobiology of disease
Yum SW,Zhang J,Scherer SS
51-2800 was used in immunocytochemistry to test if dominant Cx26 mutants interact directly with Cx30
Sat May 01 00:00:00 EDT 2010
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice.
Human molecular genetics
Schütz M,Scimemi P,Majumder P,De Siati RD,Crispino G,Rodriguez L,Bortolozzi M,Santarelli R,Seydel A,Sonntag S,Ingham N,Steel KP,Willecke K,Mammano F
51-2800 was used in immunohistochemistry to create and characterize a mouse model for human bilateral middle/high-frequency hearing loss
Wed Dec 15 00:00:00 EST 2010
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice.
Human molecular genetics
Schütz M,Scimemi P,Majumder P,De Siati RD,Crispino G,Rodriguez L,Bortolozzi M,Santarelli R,Seydel A,Sonntag S,Ingham N,Steel KP,Willecke K,Mammano F
51-2800 was used in immunohistochemistry to create and characterize a mouse model for human bilateral middle/high-frequency hearing loss
Wed Dec 15 00:00:00 EST 2010
ATP-mediated cell-cell signaling in the organ of Corti: the role of connexin channels.
Purinergic signalling
Majumder P,Crispino G,Rodriguez L,Ciubotaru CD,Anselmi F,Piazza V,Bortolozzi M,Mammano F
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunofluorescence
Tue Jun 01 00:00:00 EDT 2010
Hyperglycaemia and diabetes impair gap junctional communication among astrocytes.
ASN neuro
Gandhi GK,Ball KK,Cruz NF,Dienel GA
51-2800 was used in immunohistochemistry - frozen section to investigate the influence of experimental diabetes on gap junction channel-mediated dye transfer
Mon Mar 15 00:00:00 EDT 2010
Immunocytochemical traits of type IV fibrocytes and their possible relations to cochlear function and pathology.
Journal of the Association for Research in Otolaryngology : JARO
Adams JC
51-2800 was used in immunohistochemistry to study noise-induced loss of type IV fibrocytes
Tue Sep 01 00:00:00 EDT 2009
Tissue-specific cross-reactivity of connexin32 antibodies: problems and solutions unique to the central nervous system.
Cell communication & adhesion
Fowler SL,McLean AC,Bennett SA
51-2800 was used in western blot to discuss the limitations of using antibodies to study connexin 32 expression in the central nervous system
Tue Dec 01 00:00:00 EST 2009
Limited intravascular coupling in the rodent brainstem and retina supports a role for glia in regional blood flow.
The Journal of comparative neurology
Kuo IY,Chan-Ling T,Wojcikiewicz RJ,Hill CE
51-2800 was used in immunohistochemistry to study the extent of coupling in microvessels of the rodent brainstem and retina and the subtypes of intracellular calcium stores that mediate astrocytic signaling.
Sat Dec 20 00:00:00 EST 2008
Modulation of connexin expression and gap junction communication in astrocytes by the gram-positive bacterium S. aureus.
Glia
Esen N,Shuffield D,Syed MM,Kielian T
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Western Blot
Mon Jan 01 00:00:00 EST 2007
Modulation of connexin expression and gap junction communication in astrocytes by the gram-positive bacterium S. aureus.
Glia
Esen N,Shuffield D,Syed MM,Kielian T
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Western Blot
Mon Jan 01 00:00:00 EST 2007
Human connexin26 and connexin30 form functional heteromeric and heterotypic channels.
American journal of physiology. Cell physiology
Yum SW,Zhang J,Valiunas V,Kanaporis G,Brink PR,White TW,Scherer SS
51-2800 was used in Immunocytochemistry to investigate the interactions between connexin26 and connexin30 in the human cochlea.
Sat Sep 01 00:00:00 EDT 2007
Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus.
Neuroscience
Rash JE,Olson CO,Davidson KG,Yasumura T,Kamasawa N,Nagy JI
51-2800 was used in immunohistochemistry to determine the abundance and connexin composition of neuronal and glial gap junctions in developing and adult rat and mouse locus coeruleus
Sun Jul 29 00:00:00 EDT 2007
Expression of connexins in embryonic mouse neocortical development.
The Journal of comparative neurology
Cina C,Bechberger JF,Ozog MA,Naus CC
51-2800 was used in western blot to study of the spatial and temporal pattern of connexin expression in the developing brain.
Thu Sep 20 00:00:00 EDT 2007
Expression of connexins in embryonic mouse neocortical development.
The Journal of comparative neurology
Cina C,Bechberger JF,Ozog MA,Naus CC
51-2800 was used in western blot to study of the spatial and temporal pattern of connexin expression in the developing brain.
Thu Sep 20 00:00:00 EDT 2007
In vitro optimization of antisense oligodeoxynucleotide design: an example using the connexin gene family.
Journal of biomolecular techniques : JBT
Law LY,Zhang WV,Stott NS,Becker DL,Green CR
51-2800 was used in immunohistochemistry to design and test antisense oligodeoxynucleotides that target connexins
Fri Sep 01 00:00:00 EDT 2006
Connexin43 is overexpressed in Apc(Min/+)-mice adenomas and colocalises with COX-2 in myofibroblasts.
International journal of cancer
Husøy T,Knutsen HK,Cruciani V,Olstørn HB,Mikalsen SO,Løberg EM,Alexander J
51-2800 was used in immunohistochemistry - paraffin section to assess the expression of connexins as a function of heterozygous and homozygous Apc mutation in normal intestinal tissues and adenomas of Min-mice
Thu Sep 01 00:00:00 EDT 2005
Restoration of functional gap junctions through internal ribosome entry site-dependent synthesis of endogenous connexins in density-inhibited cancer cells.
Molecular and cellular biology
Lahlou H,Fanjul M,Pradayrol L,Susini C,Pyronnet S
Sun May 01 00:00:00 EDT 2005
Restoration of functional gap junctions through internal ribosome entry site-dependent synthesis of endogenous connexins in density-inhibited cancer cells.
Molecular and cellular biology
Lahlou H,Fanjul M,Pradayrol L,Susini C,Pyronnet S
Sun May 01 00:00:00 EDT 2005
Restoration of functional gap junctions through internal ribosome entry site-dependent synthesis of endogenous connexins in density-inhibited cancer cells.
Molecular and cellular biology
Lahlou H,Fanjul M,Pradayrol L,Susini C,Pyronnet S
Sun May 01 00:00:00 EDT 2005
Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly.
Neuroscience
Rash JE,Davidson KG,Yasumura T,Furman CS
51-2800 was used for immunogold labeling in Electron microscopy to characterise the crystalline aggregates of intramembrane proteins that comprise the aquaporin-4 "square arrays" of astrocyte and ependymocyte plasma membranes.
Tue Mar 29 00:00:00 EST 2005
Coupling of astrocyte connexins Cx26, Cx30, Cx43 to oligodendrocyte Cx29, Cx32, Cx47: Implications from normal and connexin32 knockout mice.
Glia
Nagy JI,Ionescu AV,Lynn BD,Rash JE
Mon Dec 01 00:00:00 EST 2003
Coupling of astrocyte connexins Cx26, Cx30, Cx43 to oligodendrocyte Cx29, Cx32, Cx47: Implications from normal and connexin32 knockout mice.
Glia
Nagy JI,Ionescu AV,Lynn BD,Rash JE
Mon Dec 01 00:00:00 EST 2003
Exocrine specific expression of Connexin32 is dependent on the basic helix-loop-helix transcription factor Mist1.
Journal of cell science
Rukstalis JM,Kowalik A,Zhu L,Lidington D,Pin CL,Konieczny SF
Fri Aug 15 00:00:00 EDT 2003
Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential.
Human molecular genetics
Teubner B,Michel V,Pesch J,Lautermann J,Cohen-Salmon M,Söhl G,Jahnke K,Winterhager E,Herberhold C,Hardelin JP,Petit C,Willecke K
Wed Jan 01 00:00:00 EST 2003
Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential.
Human molecular genetics
Teubner B,Michel V,Pesch J,Lautermann J,Cohen-Salmon M,Söhl G,Jahnke K,Winterhager E,Herberhold C,Hardelin JP,Petit C,Willecke K
Wed Jan 01 00:00:00 EST 2003
Connexin 26 and basic fibroblast growth factor are expressed primarily in the subpial and subependymal layers in adult brain parenchyma: roles in stem cell proliferation and morphological plasticity?
The Journal of comparative neurology
Mercier F,Hatton GI
Published figure using Connexin 26 polyclonal antibody (Product # 51-2800) in Immunohistochemistry
Mon Feb 26 00:00:00 EST 2001
Connexin26 in adult rodent central nervous system: demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43.
The Journal of comparative neurology
Nagy JI,Li X,Rempel J,Stelmack G,Patel D,Staines WA,Yasumura T,Rash JE
51-2800 was used in western blot to assess the regional, cellular, and subcellular localization of Cx26 in mouse and rat neural tissue.
Mon Dec 24 00:00:00 EST 2001
Connexin26 in adult rodent central nervous system: demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43.
The Journal of comparative neurology
Nagy JI,Li X,Rempel J,Stelmack G,Patel D,Staines WA,Yasumura T,Rash JE
51-2800 was used in western blot to assess the regional, cellular, and subcellular localization of Cx26 in mouse and rat neural tissue.
Mon Dec 24 00:00:00 EST 2001
Localization of connexin26 and connexin32 in putative CO(2)-chemosensitive brainstem regions in rat.
Respiration physiology
Solomon IC,Halat TJ,El-Maghrabi MR,O'Neal MH
Sat Dec 01 00:00:00 EST 2001
