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Invitrogen
Connexin 26 Recombinant Mouse Monoclonal Antibody (24F5)
FIGURE: 1 / 2
Connexin 26 Antibody (MA5-50243) in IHC (P)
Immunohistochemistry analysis with a Connexin 26 monoclonal antibody (Product # MA5-50243) using a dilution of 1:100 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) wa... View More
Product Details
MA5-50243
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
24F5
Immunogen
Recombinant Human GJB2 protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3092469
Target Information
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variables (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: connexin 26; Connexin-26; Cx26; Gap junction beta-2 protein; gap junction protein, beta 2, 26kDa; mutant gap junction protein beta 2
Gene Aliases: CX26; DFNA3; DFNA3A; DFNB1; DFNB1A; GJB2; HID; KID; NSRD1; PPK
UniProt ID: (Human) P29033
Entrez Gene ID: (Human) 2706
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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