Proteintech

Cyclin A2 Polyclonal Antibody

Cyclin A2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 13

Cyclin A2 Antibody (18202-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using Cyclin A2 antibody (Product # 18202-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red).

Cyclin A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cyclin A2 Antibody in Flow Cytometry (Flow)

Cyclin A2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

18202-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:8,000

View 122 publications 122 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000

Immunocytochemistry (ICC/IF)

1:400

View 4 publications 4 publications

Flow Cytometry (Flow)

Assay-dependent

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 4 publications 4 publications

Not applicable (N/A)

View 6 publications 6 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Cyclin A2 Fusion Protein Ag12765 (1-432 aa encoded by BC104783)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MLGNSAPGP ATREAGSALL ALQQTALQED QENINPEKAA PVQQPRTRAA LAVLKSGNPR GLAQQQRPKT RRVAPLKDLP VNDEHVTVPP WKANSKQPAF TIHVDEAEKE AQKKPAESQK IEREDALAFN SAISLPGPRK PLVPLDYPMD GSFESPHTMD MSIVLEDEKP VSVNEVPDYH EDIHTYLREM EVKCKPKVGY MKKQPDITNS MRAILVDWLV EVGEEYKLQN ETLHLAVNYI DRFLSSMSVL RGKLQLVGTA AMLLASKFEE IYPPEVAEFV YITDDTYTKK QVLRMEHLVL KVLTFDLAAP TVNQFLTQYF LHQQPANCKV ESLAMFLGEL SLIDADPYLK YLPSVIAGAA FHLALYTVTG QSWPESLIRK TGYTLESLKP CLMDLHQTYL KAPQHAQQSI REKYKNSKYH GVSLLNPPET LNL (1-432 aa encoded by BC104783)

Target Information

Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Sat Feb 01 00:00:00 EST 2020

EVI5 is an oncogene that regulates the proliferation and metastasis of NSCLC cells.

Journal of experimental & clinical cancer research : CR

Cai T,Zhou J,Zeng Y,Du W,Zhang Y,Liu T,Fu Y,Huang JA,Qian Q,Zhu J,Ling C,Liu Z

Mon May 11 00:00:00 EDT 2020

Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.

Journal of nanobiotechnology

Li X,Wang Y,Shi L,Li B,Li J,Wei Z,Lv H,Wu L,Zhang H,Yang B,Xu X,Jiang J

Fri Aug 14 00:00:00 EDT 2020

Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle.

Journal of Cancer

Yang R,Du Y,Wang L,Chen Z,Liu X

Wed Sep 30 00:00:00 EDT 2020

Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.

Chinese medical journal

Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

Mon Apr 20 00:00:00 EDT 2020

AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.

Cell death & disease

Chen M,Li Y,Xiao L,Dai G,Lu P,Wang Y,Rui Y

Wed Mar 18 00:00:00 EDT 2020

Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.

Clinical epigenetics

Liu Y,Zhang M,He T,Yang W,Wang L,Zhang L,Guo M

Mon Feb 10 00:00:00 EST 2020

A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.

Communications biology

Watanabe M,Saeki Y,Takahashi H,Ohtake F,Yoshida Y,Kasuga Y,Kondo T,Yaguchi H,Suzuki M,Ishida H,Tanaka K,Hatakeyama S

Tue Oct 20 00:00:00 EDT 2020

Fraxetin inhibits the growth of colon adenocarcinoma cells via the Janus kinase 2/signal transducer and activator of transcription 3 signalling pathway.

The international journal of biochemistry & cell biology

Ren S,Xing Y,Wang C,Jiang F,Liu G,Li Z,Jiang T,Zhu Y,Piao D

Sat Aug 01 00:00:00 EDT 2020

IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.

Journal of cellular physiology

Wang Z,Qi Y,Wang R,Wu W,Li Z,Wang M,Liu R,Zhang C,Li W,Wang S

Tue Dec 01 00:00:00 EST 2020

Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.