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Invitrogen
Cyclin A2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 13
Cyclin A2 Antibody (PA5-34682) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Cyclin A2 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Cyclin A2 Polyclonal Antibody (Product # PA5 34682) diluted at 1:500. Red: phalloidin, a cytoskeleton marker. Scale bar = 10 µm.
Product Details
PA5-34682
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 190 of Cyclin A2
Conjugate
Form
Liquid
Concentration
0.73 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2552034
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, IMR32, SK-N-AS, HeLa(100 µg/mL Bleomycin treatment for 24 hr), Neuro2A, PC-12, PC3.
Predicted reactivity: Rat (80%), Pig (89%), Rabbit (84%), Rhesus Monkey (98%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cyclin A; Cyclin A2 (Cyclin A); Cyclin-A; Cyclin-A2
Gene Aliases: AA408589; Ccn-1; CCN1; CCNA; CCNA2; Cyca; CycA2
UniProt ID: (Human) P20248, (Mouse) P51943
Entrez Gene ID: (Human) 890, (Rat) 114494, (Mouse) 12428
regulation of cyclin-dependent protein serine/threonine kinase activity
mitotic nuclear division
mitotic G2 DNA damage checkpoint
Ras protein signal transduction
viral process
organ regeneration
response to glucagon
cellular response to platelet-derived growth factor stimulus
cellular response to leptin stimulus
positive regulation of transcription, DNA-templated
positive regulation of fibroblast proliferation
cell division
cellular response to cocaine
cellular response to luteinizing hormone stimulus
cellular response to estradiol stimulus
cellular response to hypoxia
cellular response to nitric oxide
cochlea development
cellular response to insulin-like growth factor stimulus
regulation of G2/M transition of mitotic cell cycle
response to estradiol
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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