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Cyclin A2 Antibody (605-750) in IHC (P)
Immunohistochemistry: Human Tonsil (FFPE) stained with Mouse anti-CD75 (Cat# 605-740) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Product Details
605-750
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
E23.1
Immunogen
A synthetic peptide of human Cyclin A2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Positive control: Breast carcinoma
Cellular location: Nuclear.
Target Information
Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cyclin A; Cyclin-A; Cyclin-A2
Gene Aliases: CCN1; CCNA; CCNA2
UniProt ID: (Human) P20248
Entrez Gene ID: (Human) 890
regulation of cyclin-dependent protein serine/threonine kinase activity
mitotic nuclear division
mitotic G2 DNA damage checkpoint
Ras protein signal transduction
viral process
organ regeneration
response to glucagon
cellular response to platelet-derived growth factor stimulus
cellular response to leptin stimulus
positive regulation of transcription, DNA-templated
positive regulation of fibroblast proliferation
cell division
cellular response to cocaine
cellular response to luteinizing hormone stimulus
cellular response to estradiol stimulus
cellular response to hypoxia
cellular response to nitric oxide
cochlea development
cellular response to insulin-like growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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