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Invitrogen
Cyclophilin 40 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 7
Cyclophilin 40 Antibody (PA3-023) in ICC/IF
Immunofluorescence analysis of Cyclophilin 40 was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.01% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Cyclophilin 40 Polyclonal Antibody (Product # PA3-023) at 1:100 dilution in 0.1% BSA, incubated at 4 degree... View More
Product Details
PA3-023
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Amphibian,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length, recombinant human CyP-40 expressed in E. coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
PBS, whole serum
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_325973
Product Specific Information
PA3-023 detects cyclophilin 40 (CyP-40) from human, mouse and rat tissues and cells.
PA3-023 has been successfully used in Western blot and gel shift procedures. By Western blot, this antibody detects a 40 kDa protein representing CyP-40 from rat brain extract.
The PA3-023 immunogen is recombinant human CyP-40 expressed in E. coli.
Target Information
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; Cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; cytoplasmic cyclophilin D; EC 5.2.1.8; MGC33096; Peptidyl-prolyl cis-trans isomerase D; PPIase D; rotamase; Rotamase D; testicular tissue protein Li 147
Gene Aliases: 4930564J03Rik; CYP-40; CYP40; CYPD; PPID; Ppidl; Ppif
UniProt ID: (Human) Q08752, (Mouse) Q9CR16, (Rat) Q6DGG0
Entrez Gene ID: (Human) 5481, (Mouse) 67738, (Rat) 361967
negative regulation of transcription from RNA polymerase II promoter
protein peptidyl-prolyl isomerization
protein folding
protein complex assembly
apoptotic process
protein transport
viral release from host cell
lipid particle organization
positive regulation of apoptotic process
positive regulation of viral genome replication
positive regulation of protein secretion
chaperone-mediated protein folding
cellular response to UV-A
transport
regulation of apoptotic process
response to oxidative stress
negative regulation of apoptotic process
regulation of mitochondrial membrane potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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