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Invitrogen
Cyclophilin 40 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 8
Cyclophilin 40 Antibody (PA5-27988) in ICC/IF
Immunofluorescence analysis of 40 kDa Cyclophilin-40 (Peptidylprolyl isomerase D) was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for overnight at room temperature. The cells were labeled with Cyclophilin 40 Polyclonal Antibody (Product # PA5-27988) at 1:100 dil... View More
Product Details
PA5-27988
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 34 and 330 of Human Cyclophilin 40
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545464
Product Specific Information
Recommended positive controls: HepG2, NIH-3T3.
Predicted reactivity: Mouse (95%), Rat (94%), Pig (91%), Rhesus Monkey (97%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; cytoplasmic cyclophilin D; EC 5.2.1.8; MGC33096; Peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; PPIase D; rotamase; Rotamase D; testicular tissue protein Li 147
Gene Aliases: 4930564J03Rik; CYP-40; CYP40; CYPD; I79_011990; PPID; Ppidl; Ppif
UniProt ID: (Human) Q08752, (Mouse) Q9CR16
Entrez Gene ID: (Human) 5481, (Mouse) 67738, (Chinese hamster) 100752921
negative regulation of transcription from RNA polymerase II promoter
protein peptidyl-prolyl isomerization
protein folding
protein complex assembly
apoptotic process
protein transport
viral release from host cell
lipid particle organization
positive regulation of apoptotic process
positive regulation of viral genome replication
positive regulation of protein secretion
chaperone-mediated protein folding
cellular response to UV-A
transport
regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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