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Product Details
MA1-81910
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
Cyst24
Immunogen
Proprietary Immunogen.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
<0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_930315
Product Specific Information
Mouse anti human Cystatin C antibody, clone Cyst24 detects human Cystatin C, a member of the type 2 cystatin superfamily.
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AD8; bA218C14.4 (cystatin C); cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; epididymis secretory protein Li 2; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9
Gene Aliases: ARMD11; CST3; HEL-S-2
UniProt ID: (Human) P01034
Entrez Gene ID: (Human) 1471
defense response
negative regulation of peptidase activity
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
negative regulation of endopeptidase activity
regulation of tissue remodeling
extracellular fibril organization
cellular protein metabolic process
negative regulation of proteolysis
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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