Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
BS-3595R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse Cystatin 3, amino acids 64-140.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AD8; cystatin 3; Cystatin C (cysteine proteinase inhibitor); Cystatin-3; Cystatin-C; Cystatin3; CystatinC; MGC117328; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; RP23-250M11.9
Gene Aliases: Cst3; CYSC
UniProt ID: (Mouse) P21460, (Rat) P14841
Entrez Gene ID: (Mouse) 13010, (Rat) 25307
defense response
response to oxidative stress
positive regulation of cell proliferation
negative regulation of peptidase activity
negative regulation of endopeptidase activity
regulation of programmed cell death
extracellular fibril organization
positive regulation of DNA replication
negative regulation of proteolysis
negative regulation of elastin catabolic process
negative regulation of cell death
eye development
response to hypoxia
cell activation
apoptotic process
brain development
salivary gland development
embryo implantation
male gonad development
response to toxic substance
response to carbohydrate
response to inorganic substance
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
response to organic cyclic compound
response to nutrient levels
response to estradiol
regulation of tissue remodeling
cellular response to oxidative stress
response to drug
circadian sleep/wake cycle, REM sleep
response to axon injury
Sertoli cell development
negative regulation of blood vessel remodeling
cellular response to hydrogen peroxide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support