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FIGURE: 1 / 1
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
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Protein Aliases: 39.1; 40-kDa keratin intermediate filament; 56 kDa cytokeratin; CK-10; CK-14; CK-17; CK-19; cytokeratin 10; cytokeratin 14; cytokeratin 19; Cytokeratin-10; Cytokeratin-14; Cytokeratin-17; Cytokeratin-19; epidermal keratin 10; epidermolysis bullosa simplex, Dowling-Meara, Koebner; intermediate filament protein; K10; K14; K17; K19; keratin 10, type I; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 17, type I; keratin 19, type I; keratin complex 1, acidic, gene 10; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 17; keratin complex 1, acidic, gene 19; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 17; Keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 59 kDa; keratin, type I, 40-kd; Keratin-10; Keratin-14; Keratin-17; Keratin-19; krt10 {ECO:0000250|UniProtKB:P13645}; krt17 {ECO:0000250|UniProtKB:Q04695}; suprabasal cytokeratin 10; type I keratin KA10; Type I keratin Ka14; Type I keratin Ka17; Type I keratin Ka19
Gene Aliases: 39.1; AI626930; AI663979; BCIE; BIE; CK-17; CK10; CK14; CK19; D130054E02Rik; EBS3; EBS4; EHK; EndoC; K10; K14; K17; K19; K1C1; K1CS; Ka10; Ka14; Ka17; Ka19; KPP; Krt-1.10; Krt-1.14; Krt-1.19; Krt1-10; Krt1-14; Krt1-17; Krt1-19; KRT10; KRT14; KRT17; KRT19; NFJ; PC; PC2; PCHC1
UniProt ID: (Human) P13645, (Human) P02533, (Human) Q04695, (Human) P08727, (Mouse) P02535, (Mouse) Q61781, (Rat) Q6IFV1, (Mouse) Q9QWL7, (Rat) Q6IFU8, (Mouse) P19001, (Rat) Q63279
Entrez Gene ID: (Human) 3858, (Human) 3861, (Human) 3872, (Human) 3880, (Mouse) 16661, (Rat) 450225, (Mouse) 16664, (Rat) 287701, (Mouse) 16667, (Rat) 287702, (Mouse) 16669, (Rat) 360626
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