Proteintech

Cytokeratin 14 Monoclonal Antibody (2G1E2)

Cytokeratin 14 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

Cytokeratin 14 Antibody (60320-1-IG) in ICC/IF

Immunofluorescent analysis of A431 cells using 60320-1-IG (Cytokeratin 14 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IGG (H+L).

Cytokeratin 14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cytokeratin 14 Antibody in Western Blot (WB)

Cytokeratin 14 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

60320-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 10 publications 10 publications

Flow Cytometry (Flow)

Assay-dependent

Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Published species

Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2G1E2

Immunogen

Cytokeratin 14 Fusion Protein Ag17559 (426-472 aa encoded by BC002690)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.75 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LSSSQFSSG SQSSRDVTSS SRQIRTKVMD VHDGKVVSTH EQVLRTKN (426-472 aa encoded by BC002690)

Target Information

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

FGF4 Promotes Skin Wound Repair through p38 MAPK and GSK3β-Mediated Stabilization of Slug.

The Journal of investigative dermatology

Sun J,Zhou J,Zhou J,Xu W,Du Y,Jia Z,Shen Y,Lin X,Wang X,Bao Y,Rao Z,Dong S,Luo Y,Cong W,Jin L,Li X

Thu Jun 01 00:00:00 EDT 2023

Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition.

Cell & bioscience

Wang WS,Lin YK,Zhang F,Lei WJ,Pan F,Zhu YN,Lu JW,Zhang CY,Zhou Q,Ying H,Sun K

Wed May 18 00:00:00 EDT 2022

The immune landscape of human thymic epithelial tumors.

Nature communications

Xin Z,Lin M,Hao Z,Chen D,Chen Y,Chen X,Xu X,Li J,Wu D,Chai Y,Wu P

Sat Sep 17 00:00:00 EDT 2022

Skin chronological aging drives age-related bone loss via secretion of cystatin-A.

Nature aging

Liang W,Chen Q,Cheng S,Wei R,Li Y,Yao C,Ouyang Z,Kang D,Chen A,Liu Z,Li K,Bai X,Li Q,Huang B

Sat Oct 01 00:00:00 EDT 2022

Bone marrow mesenchymal stem cells facilitate diabetic wound healing through the restoration of epidermal cell autophagy via the HIF-1α/TGF-β1/SMAD pathway.

Stem cell research & therapy

Shi Y,Wang S,Zhang W,Zhu Y,Fan Z,Huang Y,Li F,Yang R

Fri Jul 15 00:00:00 EDT 2022

Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.

Oxidative medicine and cellular longevity

Li J,Zhao B,Dai Y,Zhang X,Chen Y,Wu X

Mon Nov 21 00:00:00 EST 2022

Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing through miR-762 mediated promotion of keratinocytes and endothelial cells migration.

Journal of nanobiotechnology

Bo Y,Yang L,Liu B,Tian G,Li C,Zhang L,Yan Y

Tue Jun 21 00:00:00 EDT 2022

Graphene Quantum Dots Disrupt Embryonic Stem Cell Differentiation by Interfering with the Methylation Level of Sox2.

Environmental science & technology

Ku T,Hao F,Yang X,Rao Z,Liu QS,Sang N,Faiola F,Zhou Q,Jiang G

Tue Mar 02 00:00:00 EST 2021

Graphene Quantum Dots Disrupt Embryonic Stem Cell Differentiation by Interfering with the Methylation Level of Sox2.

Environmental science & technology

Ku T,Hao F,Yang X,Rao Z,Liu QS,Sang N,Faiola F,Zhou Q,Jiang G

Tue Mar 02 00:00:00 EST 2021

Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.

Signal transduction and targeted therapy

Xie J,Wang Z,Fan W,Liu Y,Liu F,Wan X,Liu M,Wang X,Zeng D,Wang Y,He B,Yan M,Zhang Z,Zhang M,Hou Z,Wang C,Kang Z,Fang W,Zhang L,Lam EW,Guo X,Yan J,Zeng Y,Chen M,Liu Q

Sat Sep 04 00:00:00 EDT 2021

Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.

Signal transduction and targeted therapy

Xie J,Wang Z,Fan W,Liu Y,Liu F,Wan X,Liu M,Wang X,Zeng D,Wang Y,He B,Yan M,Zhang Z,Zhang M,Hou Z,Wang C,Kang Z,Fang W,Zhang L,Lam EW,Guo X,Yan J,Zeng Y,Chen M,Liu Q

Sat Sep 04 00:00:00 EDT 2021

Eco-Friendly and Scalable Synthesis of Fullerenols with High Free Radical Scavenging Ability for Skin Radioprotection.

Small (Weinheim an der Bergstrasse, Germany)

Zhao M,Wang C,Xie J,Ji C,Gu Z

Wed Sep 01 00:00:00 EDT 2021

Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation.

Breast cancer research : BCR

Wang D,Naydenov NG,Dozmorov MG,Koblinski JE,Ivanov AI

Tue Jan 07 00:00:00 EST 2020

Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.

iScience

Zhao J,Han Y,Ma X,Zhou Y,Yuan S,Shen Q,Ye G,Liu H,Fu P,Zhang G,Qiao B,Liu A

Fri Mar 29 00:00:00 EDT 2019

Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.

iScience

Zhao J,Han Y,Ma X,Zhou Y,Yuan S,Shen Q,Ye G,Liu H,Fu P,Zhang G,Qiao B,Liu A

Fri Mar 29 00:00:00 EDT 2019

SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer.

Stem cell reports

Zhu F,Qian W,Zhang H,Liang Y,Wu M,Zhang Y,Zhang X,Gao Q,Li Y

Tue Aug 08 00:00:00 EDT 2017

SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer.

Stem cell reports

Zhu F,Qian W,Zhang H,Liang Y,Wu M,Zhang Y,Zhang X,Gao Q,Li Y

Tue Aug 08 00:00:00 EDT 2017

Bioinformatics

Protein Aliases: CK-14; cytokeratin 14; Cytokeratin-14; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; Keratin, type I cytoskeletal 14; Keratin-14; Koebner; Type I keratin Ka14

View more View less

Gene Aliases: AI626930; CK14; EBS3; EBS4; K14; Ka14; Krt-1.14; Krt1-14; KRT14; NFJ

View more View less

UniProt ID: (Human) P02533, (Mouse) Q61781, (Rat) Q6IFV1

View more View less

Entrez Gene ID: (Human) 3861, (Mouse) 16664, (Rat) 287701, (Pig) 100737113

View more View less

Function(s)

structural constituent of cytoskeleton protein binding keratin filament binding structural molecule activity molecular_function

Process(es)

aging epithelial cell differentiation hair cycle intermediate filament bundle assembly epidermis development response to zinc ion response to ionizing radiation hemidesmosome assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Cytokeratin 14 Monoclonal Antibody (2G1E2)

Cytokeratin 14 Antibody (60320-1-IG) in ICC/IF

Product Details

60320-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!