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Invitrogen
Cytokeratin 14 Monoclonal Antibody (RCK107)
FIGURE: 1 / 1
Cytokeratin 14 Antibody (MA1-06323) in IHC (F)
Immunohistochemical analysis using indirect immunofluorescence staining of swine skin frozen tissue section with Cytokeratin 14 Antibody (Product #MA1-06323) at a dilution of 1:200. Specific staining of the basal and parabasal cells of the epidermis. No reactivity in the connective tissues.
Product Details
MA1-06323
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat,
Dog,
Human,
Pig
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
RCK107
Immunogen
Cytoskeletal preparation of TR146 epithelial cells.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
purified
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2134823
Product Specific Information
MA1-06323 detects cytokeratin 14 in human, rat, canine, and porcine samples.
MA1-06323 has sucessfully been used in Western blotting, immunocytochemistry and immunohistochemistry.
The MA1-06323 immunogen is a cytoskeletal preparation of TR146 epithelial cells.
Store at 4ºC or in small aliquots at -20ºC.
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CK-14; cytokeratin 14; Cytokeratin-14; K14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; Keratin, type I cytoskeletal 14; Keratin-14; Koebner; Type I keratin Ka14
Gene Aliases: CK14; EBS3; EBS4; K14; Ka14; Krt1-14; KRT14; NFJ
UniProt ID: (Human) P02533, (Rat) Q6IFV1
Entrez Gene ID: (Dog) 100685323, (Human) 3861, (Rat) 287701, (Pig) 100737113
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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