Proteintech

Cytokeratin 17 Polyclonal Antibody

Cytokeratin 17 Antibody in Immunocytochemistry (ICC/IF)

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Cytokeratin 17 Antibody (17516-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Methanol) fixed HepG2 cells using Cytokeratin 17-Specific antibody (Product # 17516-1-AP) at dilution of 1:600 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Cytokeratin 17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cytokeratin 17 Antibody in Western Blot (WB)

Cytokeratin 17 Antibody in Flow Cytometry (Flow)

Cytokeratin 17 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17516-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specifically against KRT17.

Target Information

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma.

Cancers

Zhou Z,Zhang G,Li T,Ai J,Li W,Zeng S,Ye M,Liu Q,Xiao J,Li Y,Tan G,Zhang X

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LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma.

Cancers

Zhou Z,Zhang G,Li T,Ai J,Li W,Zeng S,Ye M,Liu Q,Xiao J,Li Y,Tan G,Zhang X

Wed Jan 18 00:00:00 EST 2023

LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma.

Cancers

Zhou Z,Zhang G,Li T,Ai J,Li W,Zeng S,Ye M,Liu Q,Xiao J,Li Y,Tan G,Zhang X

Wed Jan 18 00:00:00 EST 2023

LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma.

Cancers

Zhou Z,Zhang G,Li T,Ai J,Li W,Zeng S,Ye M,Liu Q,Xiao J,Li Y,Tan G,Zhang X

Wed Jan 18 00:00:00 EST 2023

The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.

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Ecotoxicology and environmental safety

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Thu Sep 15 00:00:00 EDT 2022

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Keratin 17 upregulation promotes cell metastasis and angiogenesis in colon adenocarcinoma.

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Cytokeratin expression in epidermal stem cells in skin adnexal tumors.

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Keratin17 Promotes Tumor Growth and is Associated with Poor Prognosis in Gastric Cancer.

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Keratin17 Promotes Tumor Growth and is Associated with Poor Prognosis in Gastric Cancer.

Journal of Cancer

Hu H,Xu DH,Huang XX,Zhu CC,Xu J,Zhang ZZ,Zhao G

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Keratin17 Promotes Tumor Growth and is Associated with Poor Prognosis in Gastric Cancer.

Journal of Cancer

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Sun Apr 10 00:00:00 EDT 2022

Keratin17 Promotes Tumor Growth and is Associated with Poor Prognosis in Gastric Cancer.

Journal of Cancer

Hu H,Xu DH,Huang XX,Zhu CC,Xu J,Zhang ZZ,Zhao G

Sun Apr 10 00:00:00 EDT 2022

Bioinformatics

Protein Aliases: 39.1; CK-17; CK17; Cytokeratin-17; hard keratin; K17; keratin 17, type I; keratin complex 1, acidic, gene 17; Keratin, type I cytoskeletal 17; Keratin-17

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Gene Aliases: 39.1; CK-17; K17; Krt1-17; KRT17; PC; PC2; PCHC1

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UniProt ID: (Human) Q04695, (Mouse) Q9QWL7

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Entrez Gene ID: (Human) 3872, (Mouse) 16667

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Function(s)

structural constituent of cytoskeleton protein binding MHC class II receptor activity MHC class II protein binding structural molecule activity

Process(es)

morphogenesis of an epithelium signal transduction positive regulation of cell growth hair follicle morphogenesis keratinization intermediate filament organization positive regulation of translation positive regulation of hair follicle development epidermis development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Cytokeratin 17 Polyclonal Antibody

Cytokeratin 17 Antibody (17516-1-AP) in ICC/IF

Product Details

17516-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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