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NeoBiotechnologies
Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8267R)
FIGURE: 1 / 1
Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Antibody (3853-RBM12-P1ABX) in IHC (P)
Formalin-fixed, paraffin-embedded human skin stained with Cytokeratin 6A Recombinant Rabbit Monoclonal Antibody (KRT6/8267R). Inset: PBS instead of primary antibody; secondary only negative control.
Product Details
3853-RBM12-P1ABX
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
KRT6/8267R
Immunogen
Recombinant fragment (around aa1-200) of human KRT6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
Positive Control:Human tonsil or basal cell carcinoma (BCC).
Cellular Location: Cytoplasm
Target Information
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-6A; CK-6B; CK-6C; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6B; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; Cytokeratin-6B; Cytokeratin-6C; Cytokeratin-6D; Cytokeratin-6E; K6A; K6B; K6C; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 6A, , type II; keratin 6A, type II; keratin 6B, type II; keratin 6C, type II; keratin 6E; Keratin K6h; keratin, epidermal type II, K6A; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; Keratin, type II cytoskeletal 6C; Keratin-6A; Keratin-6B; Keratin-6C; keratin-like 1 (a type II keratin sequence); Type-II keratin Kb10; Type-II keratin Kb12; Type-II keratin Kb6
Gene Aliases: CK-6B; CK-6C; CK-6E; CK6A; CK6B; CK6C; CK6D; K6A; K6B; K6C; K6D; K6E; KRT6A; KRT6B; KRT6C; KRT6D; KRT6E; KRTL1; PC2; PC3; PC4; PPKNEFD
UniProt ID: (Human) P02538, (Human) P04259, (Human) P48668
Entrez Gene ID: (Human) 3853, (Human) 3854, (Human) 286887
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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