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Proteintech
Cytokeratin 6A Polyclonal Antibody
Product Details
10590-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Cytokeratin 6A Fusion Protein Ag0882 (364-564 aa encoded by BC008807)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QVTAGRHGD DLRNTKQEIA EINRMIQRLR SEIDHVKKQC ANLQAAIADA EQRGEMALKD AKNKLEGLED ALQKAKQDLA RLLKEYQELM NVKLALDVEI ATYRKLLEGE ECRLNGEGVG QVNISVVQST VSSGYGGASG VGSGLGLGGG SSYSYGSGLG VGGGFSSSSG RAIGGGLSSV GGGSSTIKYT TTSSSSRKSY KH (364-564 aa encoded by BC008807)
Target Information
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 60-kDa keratin; CK-6A; CK-6D; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; K6A; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6h; keratin, epidermal type II, K6A; Keratin, type II cytoskeletal 6A; Keratin-6-alpha; Keratin-6A; keratin-6C; mK6-alpha; type-II keratin Kb12; Type-II keratin Kb6
Gene Aliases: 2310016L08Rik; CK-6C; CK-6E; CK6A; CK6C; CK6D; K6A; K6C; K6D; Ker2; Krt2-6; Krt2-6a; Krt2-6c; Krt6; KRT6A; KRT6C; KRT6D; mK6[a]; MK6a; PC3
UniProt ID: (Human) P02538, (Mouse) P50446
Entrez Gene ID: (Human) 3853, (Mouse) 16687
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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