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NeoBiotechnologies
Cytokeratin 6A (KRT6A) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/3997R)
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Cytokeratin 6A (KRT6A) (Basal Cell Marker) Antibody (3853-RBM7-P0) in IHC (P)
Formalin-fixed, paraffin-embedded human lung adenocarcinoma stained with Cytokeratin 6A Recombinant Rabbit Monoclonal Antibody (KRT6/3997R). HIER: Tris/EDTA, pH9.0, 45 min. 2 °: HRP-polymer, 30 min. DAB, 5 min.
Product Details
3853-RBM7-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
KRT6/3997R
Immunogen
Recombinant fragment of human KRT6 (exact sequence is proprietary)
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Wet ice
Target Information
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-6A; CK-6D; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; K6A; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 6A, , type II; keratin 6A, type II; keratin K6h; keratin, epidermal type II, K6A; Keratin, type II cytoskeletal 6A; Keratin-6A; keratin-6C; type-II keratin Kb12; Type-II keratin Kb6
Gene Aliases: CK-6C; CK-6E; CK6A; CK6C; CK6D; K6A; K6C; K6D; KRT6A; KRT6C; KRT6D; PC3
UniProt ID: (Human) P02538
Entrez Gene ID: (Human) 3853
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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