Proteintech

Cytokeratin 7 Monoclonal Antibody (2E1G5)

Cytokeratin 7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cytokeratin 7 Antibody (66483-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 66483-1-IG ( CK7 antibody) at dilution of 1:1000 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Cytokeratin 7 Antibody in Western Blot (WB)

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Product Details

66483-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:10,000-1:40,000

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000

Immunocytochemistry (ICC/IF)

View 5 publications 5 publications

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

2E1G5

Immunogen

Cytokeratin 7 Fusion Protein ag7895 (1-351 aa encoded by BC002700)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specifically against KRT7.

Immunogen sequence: MSIHFSSPV FTSRSAAFSG RGAQVRLSSA RPGGLGSSSL YGLGASRPRV AVRSAYGGPV GAGIREVTIN QSLLAPLRLD ADPSLQRVRQ EESEQIKTLN NKFASFIDKV RFLEQQNKLL ETKWTLLQEQ KSAKSSRLPD IFEAQIAGLR GQLEALQVDG GRLEAELRSM QDVVEDFKNK YEDEINRRTA AENEFVVLKK DVDAAYMSKV ELEAKVDALN DEINFLRTLN ETELTELQSQ ISDTSVVLSM DNSRSLDLDG IIAEVKAQYE EMAKCSRAEA EAWYQTKFET LQAQAGKHGD DLRNTRNEIS EMNRAIQRLQ AEIDNIKNQR AKLEAAIAEA EERGELALKD AR (1-351 aa encoded by BC002700)

Target Information

Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.

The American journal of pathology

Chen X,Song QL,Wang JY,Ji R,Li ZH,Cao ML,Mu XF,Guo DY,Zhang Y,Yang J

Tue Aug 01 00:00:00 EDT 2023

A novel nude mouse model for studying the pathogenesis of endometriosis.

Experimental and therapeutic medicine

Li LP,Li ZM,Wang ZZ,Cheng YF,He DM,Chen G,Cao BN,Zou Y,Luo Y

Mon Aug 01 00:00:00 EDT 2022

Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.

Oxidative medicine and cellular longevity

Chen X,Song QL,Li ZH,Ji R,Wang JY,Ge C,Xiao ZN,Guo DY,Yang J

Tue May 24 00:00:00 EDT 2022

Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.

Oxidative medicine and cellular longevity

Chen X,Song QL,Li ZH,Ji R,Wang JY,Ge C,Xiao ZN,Guo DY,Yang J

Tue May 24 00:00:00 EDT 2022

Comprehensive analysis of placental gene-expression profiles and identification of EGFR-mediated autophagy and ferroptosis suppression in intrahepatic cholestasis of pregnancy.

Gene

Fang Y,Fang D

Fri Aug 05 00:00:00 EDT 2022

MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.

Placenta

Chen X,Song QL,Ji R,Wang JY,Li ZH,Guo D,Yin TL,Wang SJ,Yang J

Tue Feb 01 00:00:00 EST 2022

Cyclophilin A inhibits trophoblast migration and invasion in vitro and vivo through p38/ERK/JNK pathways and causes features of preeclampsia in mice.

Life sciences

Hu H,Jiang J,Chen Q,Wei S,Liu M,Chen X,Fan C,Ma J,Chen W,Wang X,Zhong M

Sun Nov 15 00:00:00 EST 2020

Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.

Human reproduction (Oxford, England)

Gou Y,Li X,Li P,Zhang H,Xu T,Wang H,Wang B,Ma X,Jiang X,Zhang Z

Mon Apr 01 00:00:00 EDT 2019

Bioinformatics

Protein Aliases: CK-7; cytokeratin 7; Cytokeratin-7; K7; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Sarcolectin; type II mesothelial keratin K7; Type-II keratin Kb7

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Gene Aliases: CK7; K2C7; K7; KRT7; SCL

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UniProt ID: (Human) P08729

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Entrez Gene ID: (Human) 3855

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Function(s)

structural molecule activity protein binding

Process(es)

viral process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Cytokeratin 7 Monoclonal Antibody (2E1G5)

Cytokeratin 7 Antibody (66483-1-IG) in IHC (P)

Product Details

66483-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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