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Product Details
68114-1-IG150UL
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1B3D4
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DCT; DOPAchrome conversion factor; dopachrome delta-isomerase; DOPAchrome isomerase; DOPAchrome oxidoreductase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); dorpachrome tautomerase; DT; L-dopachrome Delta-isomerase; L-dopachrome isomerase; L-dopachrome tautomerase; SLATY locus protein; TRP-2; TRP2; tyrosinase related protein-2; Tyrosinase-related protein 2; tyrosinase-related protein-2; tyrosine-related protein 2
Gene Aliases: DCT; DT; slaty; slt; TRP-2; TRP2; Tyrp-2; TYRP2
UniProt ID: (Human) P40126, (Pig) Q4R1H1, (Mouse) P29812
Entrez Gene ID: (Human) 1638, (Pig) 574066, (Mouse) 13190
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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