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Product Details
25203-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DDHD2 Fusion Protein Ag18373 (56-174 aa encoded by BC010504)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDQGDTPTL EEDLKKLQLS EFFDIFEKEK VDKEALALCT DRDLQEIGIP LGPRKKILNY FSTRKNSMGI KRPAPQPASG ANIPKESEFC SSSNTRNGDY LDVGIGQVSV KYPRLIYKPE (56-174 aa encoded by BC010504)
Target Information
DDHD2, also known as KIAA0725p, is a member of the intracellular phospholipase A1 (PLA1) protein family which comprises a group of enzymes that hydrolyze the sn-1 ester bond of phospholipids, producing 2-acyl-lysophospholipids and fatty acids. DDHD2 prefers phosphatidic acid as substrate and has a role in efficient membrane trafficking from the Golgi apparatus to the plasma membrane. The gene of DDHD2 maps to chromosome 8p11.23, and encodes a 711-amino-acid protein with a calculated molecular mass of 81 kDa. It has been reported that DDHD2 immunoblot analysis of various tissue extracts revealed two bands of 90 and 85 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DDHD domain containing 2; DDHD domain-containing protein 2; intracellular phospholipase A1gamma; KIAA0725p; PA-PLA1 like; Phospholipase DDHD2; SAM, WWE and DDHD domain-containing protein 1; sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1
Gene Aliases: 2010305K11Rik; DDHD2; iPLA(1)gamma; KIAA0725; mKIAA0725; SAMWD1; SPG54
UniProt ID: (Human) O94830, (Mouse) Q9CVE9
Entrez Gene ID: (Human) 23259, (Mouse) 72108, (Rat) 680971
phospholipase activity
triglyceride lipase activity
metal ion binding
molecular_function
prenylcysteine methylesterase activity
lipase activity
hydrolase activity
1-oxa-2-oxocycloheptane lactonase activity
sulfolactone hydrolase activity
3,4-dihydrocoumarin hydrolase activity
butyrolactone hydrolase activity
endosulfan lactone lactonase activity
L-ascorbate 6-phosphate lactonase activity
Ser-tRNA(Thr) hydrolase activity
Ala-tRNA(Pro) hydrolase activity
Cys-tRNA(Pro) hydrolase activity
Ser(Gly)-tRNA(Ala) hydrolase activity
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
retinyl-palmitate esterase activity
mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
methyl indole-3-acetate esterase activity
methyl salicylate esterase activity
methyl jasmonate esterase activity
hydrolase
lipase
phospholipase
metabolite interconversion enzyme
Performance Guarantee
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