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Search Thermo Fisher Scientific
Immunogen sequence: RMHLELREGL TRMSMDLKNN LLGSLRMAWK SFTRAPYPAL QASETPEETE AEPESTSEKP SDVNTEETSV AVKEEVLPIN VGMLNGGQRI DYVLQEK
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
DDHD2, also known as KIAA0725p, is a member of the intracellular phospholipase A1 (PLA1) protein family which comprises a group of enzymes that hydrolyze the sn-1 ester bond of phospholipids, producing 2-acyl-lysophospholipids and fatty acids. DDHD2 prefers phosphatidic acid as substrate and has a role in efficient membrane trafficking from the Golgi apparatus to the plasma membrane. The gene of DDHD2 maps to chromosome 8p11.23, and encodes a 711-amino-acid protein with a calculated molecular mass of 81 kDa. It has been reported that DDHD2 immunoblot analysis of various tissue extracts revealed two bands of 90 and 85 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DDHD domain-containing protein 2; intracellular phospholipase A1gamma; KIAA0725p; PA-PLA1 like; Phospholipase DDHD2; SAM, WWE and DDHD domain-containing protein 1; sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1
Gene Aliases: DDHD2; iPLA(1)gamma; KIAA0725; SAMWD1; SPG54
UniProt ID: (Human) O94830
Entrez Gene ID: (Human) 23259
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