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Invitrogen
DDIT4 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Product Details
PA5-20495
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
a 12 amino acid peptide from near the center of human RTP801.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11155415
Product Specific Information
A suggested positive control is human kidney tissue lysate.
PA5-20495 can be used with blocking peptide PEP-0615.
Target Information
DDIT4 gene ontology annotations related to this gene include cellular response to dexamethasone stimulus; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of glycolytic process; negative regulation of TOR signaling; protein-containing complex disassembly; reactive oxygen species metabolic process; response to hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dexamethasone-induced gene 2 protein; DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4; DNA-damage-inducible transcript 4 protein; HIF-1 responsive protein RTP801; HIF-1 responsive RTP801; Protein regulated in development and DNA damage response 1; REDD-1; RP11-442H21.1
Gene Aliases: 5830413E08Rik; AA415483; DDIT4; Dig2; REDD-1; REDD1; RTP801
UniProt ID: (Human) Q9NX09, (Mouse) Q9D3F7, (Rat) Q8VHZ9
Entrez Gene ID: (Human) 54541, (Mouse) 74747, (Rat) 140942
response to hypoxia
neuron migration
apoptotic process
brain development
cell proliferation
negative regulation of signal transduction
negative regulation of peptidyl-threonine phosphorylation
neuron differentiation
negative regulation of TOR signaling
negative regulation of peptidyl-serine phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
protein complex disassembly
negative regulation of glycolytic process
neurotrophin TRK receptor signaling pathway
defense response to virus
reactive oxygen species metabolic process
positive regulation of neuron death
negative regulation of intracellular signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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