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Immunogen sequence: EKKRSKLLSPY SPQTQETDSA VQKELRNQTP APSAAQTSAP SKYHRTRSGG ARDERY
Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%.
This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DIP2 disco-interacting protein 2 homolog B; DIP2 homolog B; Disco-interacting protein 2 homolog B
Gene Aliases: DIP2B; KIAA1463
UniProt ID: (Human) Q9P265
Entrez Gene ID: (Human) 57609
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