Invitrogen

DLL1 Recombinant Rabbit Monoclonal Antibody (306)

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (24) DLL1 antibodies
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Datasheet
Protocols
Questions & Answers
Tech Support

Product Details

MA5-30337

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

ELISA (ELISA)

1:5,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

306

Immunogen

Recombinant Human DLL1 protein (Met1-Gly540)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2786082

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This antibody has specificity for Human DLL1.

Target Information

Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

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Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

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UniProt ID: (Human) O00548

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Entrez Gene ID: (Human) 28514

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Function(s)
Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding
Process(es)
cell fate determination somitogenesis somite specification heart looping marginal zone B cell differentiation type B pancreatic cell development Notch signaling pathway Notch receptor processing determination of left/right symmetry compartment pattern specification regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis cell differentiation regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of interleukin-10 production negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of cell differentiation negative regulation of epidermal cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of myoblast differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of endocytosis positive regulation of transcription from RNA polymerase II promoter lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification inner ear development regulation of neurogenesis regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment left/right axis specification nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis
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