Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MIPPADSLL KYDTPVLVSR NTEKRSPKAR LLKVSPQQPG PSGSAPQPPK TKLPSTPCVP DPTKQAEEIL NAILPPREWV EDTQLWIQQV SSTPSTRMDV VHLQEQLDLK LQQRQARETG ICPVRRELYS QCFDELIREV TINCAERGLL LLRVRDEIRM TIAAYQTLYE SSVAFGMRKA LQAEQGKSDM ERKIAELETE KRDLERQVNE QKAKCEATEK RESERRQVEE KKHNEEIQFL KRTNQQLKAQ LEGIIAPKK (1-258 aa encoded by BC046117 )
This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: axonemal dynein light chain (hp28) homolog; Axonemal dynein light intermediate polypeptide 1; dJ423B22.5 (axonemal dynein light chain (hp28)); dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; hp28; Inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas
Gene Aliases: 1700023A09Rik; AW049135; dJ423B22.5; DNALI1; hp28; P28
UniProt ID: (Human) O14645, (Mouse) Q8BVN8, (Rat) Q4FZV3
Entrez Gene ID: (Human) 7802, (Mouse) 75563, (Rat) 298524
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