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Product Details
PA5-21291
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 1802 and 1865 of DOCK1
Conjugate
Form
Liquid
Concentration
0.99 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11153260
Product Specific Information
Recommended positive controls: 293T, HeLaS3, PC-12, C8D30, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Mouse (100%), Rat (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 180 kDa protein downstream of CRK; dedicator of cyto-kinesis 1; Dedicator of cytokinesis protein 1; dock 180; DOCK180; DOwnstream of CrK; RP11-82L9.1
Gene Aliases: 9130006G06Rik; AI854900; ced5; D630004B07Rik; DOCK1; DOCK180; RGD1566072
UniProt ID: (Human) Q14185, (Mouse) Q8BUR4
Entrez Gene ID: (Human) 1793, (Mouse) 330662, (Rat) 309081
phagocytosis, engulfment
apoptotic process
cytoskeleton organization
signal transduction
integrin-mediated signaling pathway
small GTPase mediated signal transduction
blood coagulation
positive regulation of epithelial cell migration
cell migration
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
hematopoietic progenitor cell differentiation
phagocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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