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DOM3Z Antibody (PA5-100141) in ICC/IF
Immunofluorescent analysis of DOM3Z in HUVEC cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and DOM3Z polyclonal antibody (Product # PA5-100141) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-100141
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DXO(Accession O77932), corresponding to amino acid residues A66-R116.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2815671
Product Specific Information
Antibody detects endogenous levels of total DOM3Z.
Target Information
This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-3' exoribonuclease DXO; Decapping and exoribonuclease protein; DeNADding enzyme DXO; Dom-3 homolog Z; DXO; NAD-capped RNA hydrolase DXO; protein Dom3Z
Gene Aliases: DOM3L; DOM3Z; DXO; NG6; RAI1
UniProt ID: (Human) Q5ST60, (Rat) Q6MG77, (Mouse) O70348
Entrez Gene ID: (Human) 1797, (Rat) 361799, (Mouse) 112403
nucleotide binding
magnesium ion binding
mRNA binding
5'-3' exonuclease activity
RNA pyrophosphohydrolase activity
molecular_function
3'-5'-exoribonuclease activity
RNA binding
nuclease activity
exonuclease activity
5'-3' exoribonuclease activity
thiamine-pyrophosphatase activity
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
UDP-2,3-diacylglucosamine hydrolase activity
bis(5'-nucleosyl)-tetraphosphatase activity
dATP pyrophosphohydrolase activity
pyrophosphatase activity
hydrolase activity
dihydroneopterin monophosphate phosphatase activity
dihydroneopterin triphosphate pyrophosphohydrolase activity
dITP diphosphatase activity
dTTP diphosphatase activity
XTP diphosphatase activity
ATP-dependent 5'-3' DNA helicase activity
phosphocholine hydrolase activity
metal ion binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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