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Product Details
PA5-112404
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Dolichol-phosphate mannosyltransferase subunit 1 protein (2-260AA)
Conjugate
Form
Liquid
Concentration
3 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867139
Target Information
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dolichol monophosphate mannose synthase; Dolichol-phosphate mannose synthase subunit 1; Dolichol-phosphate mannosyltransferase subunit 1; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase polypeptide 1 catalytic subunit; DPM synthase complex, catalytic subunit; DPM synthase subunit 1; Mannose-P-dolichol synthase subunit 1; MPD synthase; MPD synthase subunit 1; OTTMUSP00000017164; RP23-391M18.1
Gene Aliases: AI118379; AI194292; CDGIE; DPM1; MPDS
UniProt ID: (Human) O60762, (Mouse) O70152
Entrez Gene ID: (Human) 8813, (Mouse) 13480
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