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Product Details
BS-8288R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DPYD, amino acids 265-370.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase; DPD
Gene Aliases: AI315208; DHP; DHPDHASE; DPD; DPYD; E330028L06Rik
UniProt ID: (Human) E9PFN1, (Rat) O89000, (Mouse) Q8CHR6
Entrez Gene ID: (Human) 1806, (Rat) 81656, (Mouse) 99586
protein binding
dihydropyrimidine dehydrogenase (NADP+) activity
protein homodimerization activity
metal ion binding
flavin adenine dinucleotide binding
NADP binding
4 iron, 4 sulfur cluster binding
uracil binding
dihydroorotate dehydrogenase activity
iron-sulfur cluster binding
nucleotide binding
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
purine nucleobase catabolic process
pyrimidine nucleobase catabolic process
thymine catabolic process
uracil catabolic process
thymidine catabolic process
beta-alanine biosynthetic process
pyrimidine nucleoside catabolic process
oxidation-reduction process
UMP biosynthetic process
response to nutrient
circadian rhythm
uracil metabolic process
response to drug
response to glucocorticoid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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