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Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase
Gene Aliases: DHP; DHPDHASE; DPD; DPYD
UniProt ID: (Human) E9PFN1
Entrez Gene ID: (Human) 1806
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