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Product Details
H00001809-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1B8
Immunogen
DPYSL3 (NP_001378, 457 a.a. approximately 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: GNLHVTQGAG RFIPCSPFSD YVYKRIKARR KMADLHAVPR GMYDGPVFDL TTTPKGGTPA GSARGSPTRP NPPVRNLHQS GFSLSGTQVD EGVRSASKR
Target Information
DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 4; collapsin response mediator protein 4 long; CRMP-4; dihydropyrimidinase-like 3; Dihydropyrimidinase-related protein 3; DRP-3; testicular secretory protein Li 7; tuc-4; ULIP-1; Unc-33-like phosphoprotein 1
Gene Aliases: CRMP-4; CRMP4; DPYSL3; DRP-3; DRP3; LCRMP; ULIP; ULIP-1; ULIP1
UniProt ID: (Human) Q14195
Entrez Gene ID: (Human) 1809
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of cell migration
neuron development
response to axon injury
actin filament bundle assembly
protein homooligomerization
positive regulation of filopodium assembly
actin crosslink formation
cellular response to cytokine stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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