Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: A549.
Predicted reactivity: Mouse (96%), Rat (95%), Chimpanzee (98%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dihydrouridine synthase 2; dihydrouridine synthase 2-like, SMM1 homolog; hDUS2; SMM1 homolog; tRNA-dihydrouridine synthase 2-like; tRNA-dihydrouridine(20) synthase (NAD(P)(+)); tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Up-regulated in lung cancer protein 8; URLC8
Gene Aliases: DUS2; DUS2L; SMM1; URLC8
UniProt ID: (Human) Q9NX74
Entrez Gene ID: (Human) 54920
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support