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Product Details
PA5-32191
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 552 and 1208 of Human DZIP3
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2549664
Product Specific Information
Recommended positive controls: 293T, mouse kidney.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DAZ interacting protein 3, zinc finger; DAZ-interacting protein 3; DAZ-interacting protein 3 homolog; E3 ubiquitin-protein ligase DZIP3; hRUL138; human RNA-binding ubiquitin ligase of 138 kDa; protein phosphatase 1, regulatory subunit 66; RING-type E3 ubiquitin transferase DZIP3; RNA-binding RING-H2 protein-ubiquitin ligase; RNA-binding ubiquitin ligase of 138 kDa; UURF2 ubiquitin ligase; zinc finger DAZ interacting protein 3
Gene Aliases: 2310047C04Rik; 2A-HUB; 6430549P11Rik; A230104G20; DZIP3; hRUL138; KIAA0675; PPP1R66; UURF2
UniProt ID: (Human) Q86Y13, (Mouse) Q7TPV2
Entrez Gene ID: (Human) 9666, (Mouse) 224170
RNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
phosphatase binding
polyubiquitin binding
poly(A) RNA binding
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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