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Invitrogen
Desmocollin 3 Recombinant Rabbit Monoclonal Antibody (JE55-86)
FIGURE: 1 / 5
Desmocollin 3 Antibody (MA5-42507) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of of Desmocollin 3 in 293T cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with Desmocollin 3 Recombinant Monoclonal Antibody (Product # MA5-42507) at a dilution of 1:50 for 1 hour at room temperature, w... View More
Product Details
MA5-42507
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE55-86
Immunogen
Synthetic peptide within C-terminal Human Desmocollin 3
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2911648
Product Specific Information
Positive Control: Rat skin tissue lysate, A431 cell lysate, 293T, human skin tissue, mouse esophagus tissue, A431.
Subcellular Location: Cell membrane, desmosome.
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARVC10; ARVD10; Cadherin family member 3; CDHF5; CDHF6; CMD1BB; Desmocollin-3; Desmocollin-4; desmoglein-2; desmoglein-3; HT-CP
Gene Aliases: 5430426I24Rik; CDHF3; DSC; DSC1; DSC2; DSC3; DSC4; HT-CP
UniProt ID: (Human) Q14574, (Mouse) P55850
Entrez Gene ID: (Human) 1825, (Mouse) 13507, (Rat) 307563
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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