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Invitrogen
Dopamine Transporter Polyclonal Antibody
Product Details
PA1-4656
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region of human SLC6A3 conjugated to KLH
Conjugate
Form
Liquid
Concentration
0.30 mg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_558680
Product Specific Information
This antibody is specific for the ~88 kDa DAT protein in Western blots of SDS solubilized human and mouse striatal samples and in IHC applications with formaldehyde-fixed human and monkey (Macaque) brain sections.
Target Information
The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DA transporter; DAT; dopamine transporter 1; Sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Solute carrier family 6 member 3; solute carrier family 6, member 3
Gene Aliases: DAT; DAT1; PKDYS; SLC6A3
UniProt ID: (Human) Q01959, (Rat) P23977, (Mouse) Q61327
Entrez Gene ID: (Human) 6531, (Rat) 24898, (Mouse) 13162
protease binding
receptor binding
dopamine transmembrane transporter activity
dopamine:sodium symporter activity
protein binding
drug binding
monoamine transmembrane transporter activity
protein complex binding
dopamine binding
metal ion binding
protein N-terminus binding
protein phosphatase 2A binding
neurotransmitter:sodium symporter activity
symporter activity
primary active transporter
aging
lactation
sensory perception of smell
locomotory behavior
response to iron ion
monoamine transport
dopamine transport
adenohypophysis development
response to nicotine
positive regulation of multicellular organism growth
regulation of dopamine metabolic process
neurotransmitter biosynthetic process
response to cocaine
dopamine biosynthetic process
dopamine catabolic process
response to drug
response to ethanol
dopamine uptake involved in synaptic transmission
response to cAMP
prepulse inhibition
ammonium transmembrane transport
dopamine uptake
neurotransmitter transport
response to organic cyclic compound
cation transmembrane transport
transport
organic cation transport
sodium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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