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Drebrin Antibody (MA5-28542) in Flow
Separation of REH cells stained using anti-human Drebrin (DBN-N-03) PE antibody (10 µL reagent per million cells in 100 µL of cell suspension, red-filled) from REH cells stained using mouse IgG1 isotype control (MOPC-21) PE Monoclonal antibody (Product # MA5-28542), concentration in sample 5 µg/mL (same as Drebrin PE concentration, black-dashed) in flow cytometry analysis (intracellular staining) of REH cell suspension.
Product Details
MA5-28542
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
DBN-N-03
Immunogen
human drebrin (aa 1-326, N terminal)
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745501
Product Specific Information
This antibody recognizes drebrin, an approximately 100-125 kDa intracellular regulator of actin cytoskeleton.
Recommended dilution is for 100 µL of whole blood or 1x10^6 cells in suspension.
Target Information
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmentally-regulated brain protein; DKFZp434D064; Drebrin; drebrin E; drebrin E2; drebrin-1
Gene Aliases: D0S117E; DBN1
UniProt ID: (Human) Q16643
Entrez Gene ID: (Human) 1627
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