Product References
APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain.
Molecular cell
Ferguson CJ,Urso O,Bodrug T,Gassaway BM,Watson ER,Prabu JR,Lara-Gonzalez P,Martinez-Chacin RC,Wu DY,Brigatti KW,Puffenberger EG,Taylor CM,Haas-Givler B,Jinks RN,Strauss KA,Desai A,Gabel HW,Gygi SP,Schulman BA,Brown NG,Bonni A
MA5-11496 was used in Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot to investigate ubiquitin signalling and APC7 in mammalian brain development.
Thu Jan 06 00:00:00 EST 2022
NRAS mutant E132K identified in young-onset sporadic colorectal cancer and the canonical mutants G12D and Q61K affect distinct oncogenic phenotypes.
Scientific reports
Yu RTD,Garcia RL
Published figure using E-cadherin monoclonal antibody (Product # MA5-11496) in Immunocytochemistry
Fri Jul 03 00:00:00 EDT 2020
NRAS mutant E132K identified in young-onset sporadic colorectal cancer and the canonical mutants G12D and Q61K affect distinct oncogenic phenotypes.
Scientific reports
Yu RTD,Garcia RL
Published figure using E-cadherin monoclonal antibody (Product # MA5-11496) in Immunocytochemistry
Fri Jul 03 00:00:00 EDT 2020
MicroRNA-203 Inhibits Long Noncoding RNA HOTAIR and Regulates Tumorigenesis through Epithelial-to-mesenchymal Transition Pathway in Renal Cell Carcinoma.
Molecular cancer therapeutics
Dasgupta P,Kulkarni P,Majid S,Shahryari V,Hashimoto Y,Bhat NS,Shiina M,Deng G,Saini S,Tabatabai ZL,Yamamura S,Tanaka Y,Dahiya R
MA5-11496 was used in Western Blotting to investigate the role of the miR-203-HOTAIR interaction in the suppression of renal cell carcinoma.
Tue May 01 00:00:00 EDT 2018
Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin.
Oncogene
Matsuura K,Huang NJ,Cocce K,Zhang L,Kornbluth S
MA511496 was used in western blot to identify homologous to the E6-AP carboxyl terminus as a ubiquitin ligase for modulator of apoptosis protein 1
Thu Mar 23 00:00:00 EDT 2017
MicroRNA-720 Regulates E-cadherin-αE-catenin Complex and Promotes Renal Cell Carcinoma.
Molecular cancer therapeutics
Bhat NS,Colden M,Dar AA,Saini S,Arora P,Shahryari V,Yamamura S,Tanaka Y,Kato T,Majid S,Dahiya R
MA5-11496 was used in Western Blotting to suggest that therapeutic regulation of miR-720 may provide an opportunity to regulate EMT and metastasis in RCC.
Fri Dec 01 00:00:00 EST 2017
Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.
Nature communications
Feringa FM,Krenning L,Koch A,van den Berg J,van den Broek B,Jalink K,Medema RH
MA5-11496 was used in western blot to describe a novel irreversible DNA-damage response in antephase
Fri Aug 26 00:00:00 EDT 2016
Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20.
Journal of cell science
Boekhout M,Wolthuis R
MA5-11496 was used in western blot to explore how Nek2 isoform A affects anaphase-promoting complex/cyclosome containing Cdc20.
Wed Apr 15 00:00:00 EDT 2015
MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C.
Biology open
Voets E,Wolthuis R
MA5-11496 was used in western blot to study the effect of MASTL on cyclin B1 degradation and its mechanism
Fri Mar 06 00:00:00 EST 2015
APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.
The EMBO journal
Lafranchi L,de Boer HR,de Vries EG,Ong SE,Sartori AA,van Vugt MA
Published figure using E-cadherin monoclonal antibody (Product # MA5-11496) in Western Blot
Mon Dec 01 00:00:00 EST 2014
Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells.
Cellular and molecular life sciences : CMLS
Parrillas V,Martínez-Muñoz L,Holgado BL,Kumar A,Cascio G,Lucas P,Rodríguez-Frade JM,Malumbres M,Carrera AC,van Wely KH,Mellado M
MA5-11496 was used in Western Blotting to elucidate a mechanism by which suppressor of cytokine signalling 1 inhibits the in vivo and in vitro expansion of human melanoma cells.
Fri Feb 01 00:00:00 EST 2013
The APC/C activator Cdh1 regulates the G2/M transition during differentiation of placental trophoblast stem cells.
Biochemical and biophysical research communications
Naoe H,Chiyoda T,Ishizawa J,Masuda K,Saya H,Kuninaka S
MA5-11496 was used in western blot to study the role of Cdh1 in regulating G2/M transition during placental differentiation
Fri Jan 11 00:00:00 EST 2013
Skp1-Cul1-F-box ubiquitin ligase (SCF(βTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry.
The Journal of biological chemistry
Burrows AC,Prokop J,Summers MK
MA5-11496 was used in western blot to study the role of Skp1-Cul1-F-box ubiquitin ligase in regulating the levels of USP37 and cell cycle progression
Fri Nov 09 00:00:00 EST 2012
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.
Nature cell biology
Binné UK,Classon MK,Dick FA,Wei W,Rape M,Kaelin WG,Näär AM,Dyson NJ
MA5-11496 was used in western blot to examine the interaction between retinoblastoma protein and anaphase-promoting complex
Thu Feb 01 00:00:00 EST 2007
Inactivation of human MAD2B in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents.
Cancer research
Cheung HW,Chun AC,Wang Q,Deng W,Hu L,Guan XY,Nicholls JM,Ling MT,Chuan Wong Y,Tsao SW,Jin DY,Wang X
MA5-11496 was used in western blot to study the role of MAD2B in cellular sensitivity to DNA-damaging anticancer drugs in nasopharyngeal carcinoma cells
Sat Apr 15 00:00:00 EDT 2006
DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint.
Proceedings of the National Academy of Sciences of the United States of America
Huang X,Tran T,Zhang L,Hatcher R,Zhang P
MA5-11496 was used in western blot to study the role of Chk1 in mediating DNA damage-induced mitotic catastrophe
Tue Jan 25 00:00:00 EST 2005
Human cytomegalovirus inactivates the G0/G1-APC/C ubiquitin ligase by Cdh1 dissociation.
Cell cycle (Georgetown, Tex.)
Wiebusch L,Bach M,Uecker R,Hagemeier C
MA5-11496 was used in western blot to study the mechanism by which human cytomegalovirus inactivates the G0/G1-APC/C ubiquitin ligase
Sat Oct 01 00:00:00 EDT 2005