Proteintech

ECHS1 Monoclonal Antibody (2B9D5)

ECHS1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 12

ECHS1 Antibody (66117-1-IG) in ICC/IF

Immunofluorescent analysis of HepG2 cells using 66117-1-IG (ECHS1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IGG (H+L).

ECHS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ECHS1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

66117-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:20,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:1,000

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

2B9D5

Immunogen

ECHS1 Fusion Protein Ag16775 (1-290 aa encoded by BC008906)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.21 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAALRVLLS CVRGPLRPPV RCPAWRPFAS GANFEYIIAE KRGKNNTVGL IQLNRPKALN ALCDGLIDEL NQALKIFEED PAVGAIVLTG GDKAFAAGAD IKEMQNLSFQ DCYSSKFLKH WDHLTQVKKP VIAAVNGYAF GGGCELAMMC DIIYAGEKAQ FAQPEILIGT IPGAGGTQRL TRAVGKSLAM EMVLTGDRIS AQDAKQAGLV SKICPVETLV EEAIQCAEKI ASNSKIVVAM AKESVNAAFE MTLTEGSKLE KKLFYSTFAT DDRKEGMTAF VEKRKANFKD Q (1-290 aa encoded by BC008906)

Target Information

The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.

FEBS open bio

Li Z,Shen W,Wu G,Qin C,Zhang Y,Wang Y,Song G,Xiao C,Zhang X,Deng G,Wang R,Wang X

Thu Jul 01 00:00:00 EDT 2021

ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.

Cell death & disease

Li R,Hao Y,Wang Q,Meng Y,Wu K,Liu C,Xu L,Liu Z,Zhao L

Wed Oct 06 00:00:00 EDT 2021

ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.

Cell death & disease

Li R,Hao Y,Wang Q,Meng Y,Wu K,Liu C,Xu L,Liu Z,Zhao L

Wed Oct 06 00:00:00 EDT 2021

ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.

Cell death & disease

Li R,Hao Y,Wang Q,Meng Y,Wu K,Liu C,Xu L,Liu Z,Zhao L

Wed Oct 06 00:00:00 EDT 2021

Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.

Annals of clinical and translational neurology

Haack TB,Jackson CB,Murayama K,Kremer LS,Schaller A,Kotzaeridou U,de Vries MC,Schottmann G,Santra S,Büchner B,Wieland T,Graf E,Freisinger P,Eggimann S,Ohtake A,Okazaki Y,Kohda M,Kishita Y,Tokuzawa Y,Sauer S,Memari Y,Kolb-Kokocinski A,Durbin R,Hasselmann O,Cremer K,Albrecht B,Wieczorek D,Engels H,Hahn D,Zink AM,Alston CL,Taylor RW,Rodenburg RJ,Trollmann R,Sperl W,Strom TM,Hoffmann GF,Mayr JA,Meitinger T,Bolognini R,Schuelke M,Nuoffer JM,Kölker S,Prokisch H,Klopstock T

Fri May 01 00:00:00 EDT 2015

Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.

Annals of clinical and translational neurology

Fri May 01 00:00:00 EDT 2015

Up-regulation of fatty acid oxidation in the ligament as a contributing factor of ankylosing spondylitis: A comparative proteomic study.

Journal of proteomics

Xu WD,Yang XY,Li DH,Zheng KD,Qiu PC,Zhang W,Li CY,Lei KF,Yan GQ,Jin SW,Wang JG

Thu Jan 15 00:00:00 EST 2015

Up-regulation of fatty acid oxidation in the ligament as a contributing factor of ankylosing spondylitis: A comparative proteomic study.

Journal of proteomics

Xu WD,Yang XY,Li DH,Zheng KD,Qiu PC,Zhang W,Li CY,Lei KF,Yan GQ,Jin SW,Wang JG

Thu Jan 15 00:00:00 EST 2015

Bioinformatics

Protein Aliases: ECHS1; enoyl CoA hydratase, short chain, 1, mitochondrial; enoyl Coenzyme A hydratase, short chain, 1, mitochondrial; Enoyl-CoA hydratase 1; Enoyl-CoA hydratase, mitochondrial; enoyl-CoA hydratase, short chain, 1, mitochondrial; mECH; SCEH; short chain enoyl-CoA hydratase; Short-chain enoyl-CoA hydratase

View more View less

Gene Aliases: ECHS1; ECHS1D; SCEH

View more View less

UniProt ID: (Human) P30084

View more View less

Entrez Gene ID: (Human) 1892

View more View less

Function(s)

enoyl-CoA hydratase activity protein binding hydratase

Process(es)

fatty acid beta-oxidation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

ECHS1 Monoclonal Antibody (2B9D5)

ECHS1 Antibody (66117-1-IG) in ICC/IF

Product Details

66117-1-IG

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!