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Product Details
PA5-65009
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human EDEM3. Recombinant protein control fragment (Product #RP-105774).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664684
Product Specific Information
Immunogen sequence: SSQEVDLVDQE SSEENSLNSH PESLSLADMD NAASISPSEQ TSNPTENHET TNLNGECTDL DNQLQEQSET EEDSNPNVSW GKKVQPIDSI LADWNEDIEA FEMMEKDE
Highest antigen sequence identity to the following orthologs - mouse 72%, rat 26%.
Target Information
Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-1,2-mannosidase EDEM3; ER degradation enhancer, mannosidase alpha-like 3; ER degradation-enhancing -mannosidase-like protein 3; ER degradation-enhancing alpha-mannosidase-like 3; ER degradation-enhancing alpha-mannosidase-like protein 3
Gene Aliases: C1orf22; EDEM3
UniProt ID: (Human) Q9BZQ6
Entrez Gene ID: (Human) 80267
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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