Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: IYKIPRASGT QLAAPRDALE VYDVPPTALR VPSSGPYDCP ASFSHPLTRV APQPPGEDDA PYDVPLTPKP PAELEPDLEW EGGREPGPPI YAAPSNLKRA SALLNLYEAP EELLADGEGG GTDEGIYDVP LLGPEAPPSP EPPGALAS
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cas scaffolding protein family member 3; Embryonal Fyn-associated substrate; hEFS; signal transduction protein (SH3 containing)
Gene Aliases: CAS3; CASS3; EFS; EFS1; EFS2; HEFS; SIN
UniProt ID: (Human) O43281
Entrez Gene ID: (Human) 10278
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