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Product Details
PA5-83116
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EGR1. Recombinant protein control fragment (Product #RP-105819).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790272
Product Specific Information
Immunogen sequence: IFPEPQSQAF PGSAGTALQY PPPAYPAAKG GFQVPMIPDY LFPQQQGDLG LGTPDQKPFQ GLESRTQQPS LTPLSTIKAF ATQSGSQDLK ALNTSYQSQL I
Target Information
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AT225; Early growth response protein 1; EGR-1; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24
Gene Aliases: AT225; EGR1; G0S30; KROX-24; KROX24; NGFI-A; TIS8; ZIF-268; ZNF225
UniProt ID: (Human) P18146
Entrez Gene ID: (Human) 1958
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
histone acetyltransferase binding
sequence-specific DNA binding
metal ion binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to glucose
T cell differentiation
BMP signaling pathway
response to insulin
regulation of protein sumoylation
skeletal muscle cell differentiation
regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
type I interferon signaling pathway
regulation of transcription from RNA polymerase II promoter in response to hypoxia
interleukin-1-mediated signaling pathway
cellular response to gamma radiation
cellular response to heparin
cellular response to mycophenolic acid
glomerular mesangial cell proliferation
positive regulation of glomerular metanephric mesangial cell proliferation
negative regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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