Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 86%; Dog: 86%; Guinea Pig: 85%; Horse: 92%; Human: 92%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.
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Protein Aliases: E74-like factor 5; elf-5; Epithelium specific Ets-2; ETS-related transcription factor Elf-5
Gene Aliases: Elf5; ESE-2; ESE-5; ESE-5.
UniProt ID: (Mouse) Q8VDK3
Entrez Gene ID: (Mouse) 13711
Molecular Function: winged helix/forkhead transcription factor
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