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EPCR Antibody (PA5-100503) in ICC/IF
Immunofluorescent analysis of EPCR in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and EPCR polyclonal antibody (Product # PA5-100503) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-100503
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PROCR(Accession Q9UNN8), corresponding to amino acid residues T174-G224.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850012
Product Specific Information
Antibody detects endogenous levels of total EPCR.
Target Information
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activated protein C receptor; APC receptor; bA42O4.2; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; Centrocyclin; Centrosomal protein CCD41; Endothelial cell protein C receptor; Endothelial protein C receptor; protein C receptor, endothelial
Gene Aliases: AI325044; CCCA; CCD41; EPCR; PROCR
UniProt ID: (Human) Q96CB3, (Rat) Q4V8I1, (Mouse) Q64695
Entrez Gene ID: (Human) 10544, (Rat) 362248, (Mouse) 19124
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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