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Product Details
A301-733A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Between 846 and 896
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AF-1p protein; ALL1 fused gene from chromosome 1; Epidermal growth factor receptor substrate 15; Protein AF-1p; Protein Eps15
Gene Aliases: AF-1P; AF1P; EPS15; MLLT5
UniProt ID: (Human) P42566
Entrez Gene ID: (Human) 2060
Golgi to endosome transport
epidermal growth factor receptor signaling pathway
cell proliferation
protein transport
vesicle organization
receptor-mediated endocytosis of virus by host cell
endocytic recycling
negative regulation of epidermal growth factor receptor signaling pathway
viral entry into host cell
clathrin coat assembly
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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