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Product Details
21243-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EPS15R Fusion Protein Ag15735 (351-597 aa encoded by BC142716)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PQVLSPDMV PPSERGTPGP DSSGSLGSGE FTGVKELDDI SQEIAQLQRE KYSLEQDIRE KEEAIRQKTS EVQELQNDLD RETSSLQELE AQKQDAQDRL DEMDQQKAKL RDMLSDVRQK CQDETQMISS LKTQIQSQES DLKSQEDDLN RAKSELNRLQ QEETQLEQSI QAGRVQLETI IKSLKSTQDE INQARSKLSQ LHESRQEAHR SLEQYDQVLD GAHGASLTDL ANLSEGVSLA ERGSFGAM (351-597 aa encoded by BC142716)
Target Information
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epidermal growth factor receptor pathway substrate 15-like 1; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15-related protein; Eps15R
Gene Aliases: EPS15L1; EPS15R
UniProt ID: (Human) Q9UBC2
Entrez Gene ID: (Human) 58513
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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