Invitrogen

EPX Polyclonal Antibody

1 Published Figure

1 Reference

View all (12) EPX antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)
Published Figures (1)

FIGURE: 1 / 3

EPX Antibody (PA5-42062) in WB

Western blot analysis of MCF7 cell lysate using an anti-EPX polyclonal antibody (Product # PA5-42062). Lane 1) Primary Antibody; Lane 2) Primary Antibody + Blocking Peptide.

Product Image Gallery

Product Details

PA5-42062

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human EPX

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2609489

Product Specific Information

Peptide sequence: LAFRFGHTML QPFMFRLDSQ YRASAPNSHV PLSSAFFASW RIVYEGGIDP

Sequence homology: Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Target Information

EPX belongs to the peroxidase family, XPO subfamily. Defects in EPX are the cause of eosinophil peroxidase deficiency (EPD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes.

Journal of leukocyte biology

Jeong BM,Walker MT,Rodriguez R,Coden ME,Nagasaka R,Doan TC,Politanska Y,Abdala-Valencia H,Berdnikovs S

PA5-42062 was used in Western Blotting to discover an unexpected hematopoietic flexibility of a dominant population of multipotent myeloid cells, typically categorized as neutrophils, but with the previously unknown plasticity to contribute to mature pools of eosinophils and monocytes.

Sat Jan 01 00:00:00 EST 2022

More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes.

Journal of leukocyte biology

Jeong BM,Walker MT,Rodriguez R,Coden ME,Nagasaka R,Doan TC,Politanska Y,Abdala-Valencia H,Berdnikovs S

Sat Jan 01 00:00:00 EST 2022

Bioinformatics

Protein Aliases: Eosinophil peroxidase; EPO; EPX PEN; PERE

View more View less

Gene Aliases: EPER; EPO; EPP; EPX; EPX-PEN; EPXD

View more View less

UniProt ID: (Human) P11678

View more View less

Entrez Gene ID: (Human) 8288

View more View less

Function(s)

peroxidase activity heme binding metal ion binding peroxidase

Process(es)

defense response to nematode response to oxidative stress negative regulation of interleukin-10 production negative regulation of interleukin-5 production positive regulation of interleukin-4 production hydrogen peroxide catabolic process oxidation-reduction process eosinophil migration cellular oxidant detoxification

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

EPX Polyclonal Antibody

EPX Antibody (PA5-42062) in WB

Product Details

PA5-42062

Western Blot (WB)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!