Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute at 0.5 mg/mL in sterile PBS.
ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endothelial cell-selective adhesion molecule
Gene Aliases: 2310008D05Rik; Esam; Esam1; W117m
UniProt ID: (Mouse) Q925F2
Entrez Gene ID: (Mouse) 69524
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