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Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
This antibody is predicted to react with Monkey, Bat andHorse
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
EVI1 (MECOM) is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression of the EVI1 gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AML1-EVI-1 fusion protein; Ecotropic virus integration site 1 protein homolog; EVI-1; Histone-lysine N-methyltransferase MECOM; MDS1 and EVI1 complex locus protein; MDS1 and EVI1 complex locus protein MDS1; MGC163392; MGC97004; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome-associated protein 1; oncogene EVI1; OTTHUMP00000213163; OTTHUMP00000213164; OTTHUMP00000213165; OTTHUMP00000213187; OTTHUMP00000213192; PR domain 3; zinc finger protein Evi1
Gene Aliases: AML1-EVI-1; EVI1; MDS1; MDS1-EVI1; MECOM; PRDM3; RUSAT2
UniProt ID: (Human) Q03112
Entrez Gene ID: (Human) 2122
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